Schiffer CA - Search Results

1

A call to arms: Unifying the fight against resistance.

Kaushansky A, Hedstrom L, Goldman A, Singh J, Yang PL, Rathod PK, Cynamon M, Wodarz D, Mahadevan D, Tomaras A, Navia MA, Schiffer CA. Kaushansky A, et al. Among authors: schiffer ca. Sci Signal. 2018 Oct 23;11(553):eaav0442. doi: 10.1126/scisignal.aav0442. Sci Signal. 2018. PMID: 30352947 Free PMC article.

2

The challenge of developing robust drugs to overcome resistance.

Anderson AC, Pollastri MP, Schiffer CA, Peet NP. Anderson AC, et al. Among authors: schiffer ca. Drug Discov Today. 2011 Sep;16(17-18):755-61. doi: 10.1016/j.drudis.2011.07.001. Epub 2011 Jul 19. Drug Discov Today. 2011. PMID: 21784168 Free PMC article.

3

Cooperative effects of drug-resistance mutations in the flap region of HIV-1 protease.

Foulkes-Murzycki JE, Rosi C, Kurt Yilmaz N, Shafer RW, Schiffer CA. Foulkes-Murzycki JE, et al. Among authors: schiffer ca. ACS Chem Biol. 2013 Mar 15;8(3):513-8. doi: 10.1021/cb3006193. Epub 2012 Dec 27. ACS Chem Biol. 2013. PMID: 23252515 Free PMC article.

4

Drug Design Strategies to Avoid Resistance in Direct-Acting Antivirals and Beyond.

Matthew AN, Leidner F, Lockbaum GJ, Henes M, Zephyr J, Hou S, Rao DN, Timm J, Rusere LN, Ragland DA, Paulsen JL, Prachanronarong K, Soumana DI, Nalivaika EA, Kurt Yilmaz N, Ali A, Schiffer CA. Matthew AN, et al. Among authors: schiffer ca. Chem Rev. 2021 Mar 24;121(6):3238-3270. doi: 10.1021/acs.chemrev.0c00648. Epub 2021 Jan 7. Chem Rev. 2021. PMID: 33410674 Free PMC article. Review.

5

Introduction: Drug Resistance.

Kurt Yilmaz N, Schiffer CA. Kurt Yilmaz N, et al. Among authors: schiffer ca. Chem Rev. 2021 Mar 24;121(6):3235-3237. doi: 10.1021/acs.chemrev.1c00118. Chem Rev. 2021. PMID: 33757288 Free PMC article. No abstract available.

6

Call for Papers: Drug Resistance in Infectious Diseases and Beyond.

Schiffer CA, Hazuda DJ. Schiffer CA, et al. ACS Infect Dis. 2022 Apr 8;8(4):665-666. doi: 10.1021/acsinfecdis.2c00103. Epub 2022 Mar 9. ACS Infect Dis. 2022. PMID: 35263097 No abstract available.

7

Drug resistance conferred by mutations outside the active site through alterations in the dynamic and structural ensemble of HIV-1 protease.

Ragland DA, Nalivaika EA, Nalam MN, Prachanronarong KL, Cao H, Bandaranayake RM, Cai Y, Kurt-Yilmaz N, Schiffer CA. Ragland DA, et al. Among authors: schiffer ca. J Am Chem Soc. 2014 Aug 27;136(34):11956-63. doi: 10.1021/ja504096m. Epub 2014 Aug 18. J Am Chem Soc. 2014. PMID: 25091085 Free PMC article.

8

Citrullination of NF-κB p65 promotes its nuclear localization and TLR-induced expression of IL-1β and TNFα.

Sun B, Dwivedi N, Bechtel TJ, Paulsen JL, Muth A, Bawadekar M, Li G, Thompson PR, Shelef MA, Schiffer CA, Weerapana E, Ho IC. Sun B, et al. Among authors: schiffer ca. Sci Immunol. 2017 Jun 9;2(12):eaal3062. doi: 10.1126/sciimmunol.aal3062. Sci Immunol. 2017. PMID: 28783661 Free PMC article.

9

Resistance outside the substrate envelope: hepatitis C NS3/4A protease inhibitors.

Özen A, Prachanronarong K, Matthew AN, Soumana DI, Schiffer CA. Özen A, et al. Among authors: schiffer ca. Crit Rev Biochem Mol Biol. 2019 Feb;54(1):11-26. doi: 10.1080/10409238.2019.1568962. Epub 2019 Mar 1. Crit Rev Biochem Mol Biol. 2019. PMID: 30821513 Free PMC article. Review.

10

NMR and MD studies combined to elucidate inhibitor and water interactions of HIV-1 protease and their modulations with resistance mutations.

Ishima R, Kurt Yilmaz N, Schiffer CA. Ishima R, et al. Among authors: schiffer ca. J Biomol NMR. 2019 Jul;73(6-7):365-374. doi: 10.1007/s10858-019-00260-6. Epub 2019 Jun 26. J Biomol NMR. 2019. PMID: 31243634 Free PMC article.

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