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Screening of Chelidonium majus isoquinoline alkaloids reveals berberine and chelidonine as selective ligands for the nuclear receptors RORβ and HNF4α, respectively.
Arch Pharm (Weinheim). 2024 Mar 19:e2300756. doi: 10.1002/ardp.202300756. Online ahead of print.
Arch Pharm (Weinheim). 2024.
PMID: 38501877
A Fluorescence-Based Reporter Gene Assay to Characterize Nuclear Receptor Modulators.
Schallmayer E, Merk D.
Schallmayer E, et al.
Methods Mol Biol. 2023;2706:125-135. doi: 10.1007/978-1-0716-3397-7_9.
Methods Mol Biol. 2023.
PMID: 37558945
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Development of a Potent Nurr1 Agonist Tool for In Vivo Applications.
Vietor J, Gege C, Stiller T, Busch R, Schallmayer E, Kohlhof H, Höfner G, Pabel J, Marschner JA, Merk D.
Vietor J, et al. Among authors: schallmayer e.
J Med Chem. 2023 May 11;66(9):6391-6402. doi: 10.1021/acs.jmedchem.3c00415. Epub 2023 Apr 26.
J Med Chem. 2023.
PMID: 37127285
Free PMC article.
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Mechanistic Impact of Different Ligand Scaffolds on FXR Modulation Suggests Avenues to Selective Modulators.
Heering J, Jores N, Kilu W, Schallmayer E, Peelen E, Muehler A, Kohlhof H, Vitt D, Linhard V, Gande SL, Chaikuad A, Sreeramulu S, Schwalbe H, Merk D.
Heering J, et al. Among authors: schallmayer e.
ACS Chem Biol. 2022 Nov 18;17(11):3159-3168. doi: 10.1021/acschembio.2c00599. Epub 2022 Nov 1.
ACS Chem Biol. 2022.
PMID: 36318238
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Oxaprozin Analogues as Selective RXR Agonists with Superior Properties and Pharmacokinetics.
Schierle S, Chaikuad A, Lillich FF, Ni X, Woltersdorf S, Schallmayer E, Renelt B, Ronchetti R, Knapp S, Proschak E, Merk D.
Schierle S, et al. Among authors: schallmayer e.
J Med Chem. 2021 Apr 22;64(8):5123-5136. doi: 10.1021/acs.jmedchem.1c00235. Epub 2021 Apr 1.
J Med Chem. 2021.
PMID: 33793232
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