Sarma K - Search Results

1

SF3B1 homeostasis is critical for survival and therapeutic response in T cell leukemia.

Han C, Khodadadi-Jamayran A, Lorch AH, Jin Q, Serafin V, Zhu P, Politanska Y, Sun L, Gutierrez-Diaz BT, Pryzhkova MV, Abdala-Valencia H, Bartom ET, Buldini B, Basso G, Velu SE, Sarma K, Mattamana BB, Cho BK, Obeng RC, Goo YA, Jordan PW, Tsirigos A, Zhou Y, Ntziachristos P. Han C, et al. Among authors: sarma k. Sci Adv. 2022 Jan 21;8(3):eabj8357. doi: 10.1126/sciadv.abj8357. Epub 2022 Jan 21. Sci Adv. 2022. PMID: 35061527 Free PMC article.

2

TET deficiency perturbs mature B cell homeostasis and promotes oncogenesis associated with accumulation of G-quadruplex and R-loop structures.

Shukla V, Samaniego-Castruita D, Dong Z, González-Avalos E, Yan Q, Sarma K, Rao A. Shukla V, et al. Among authors: sarma k. Nat Immunol. 2022 Jan;23(1):99-108. doi: 10.1038/s41590-021-01087-w. Epub 2021 Dec 22. Nat Immunol. 2022. PMID: 34937926 Free PMC article.

3

Targeted Nuclease Approaches for Mapping Native R-Loops.

Wulfridge P, Yan Q, Sarma K. Wulfridge P, et al. Among authors: sarma k. Methods Mol Biol. 2022;2528:373-380. doi: 10.1007/978-1-0716-2477-7_25. Methods Mol Biol. 2022. PMID: 35704205

4

Proximity labeling identifies a repertoire of site-specific R-loop modulators.

Yan Q, Wulfridge P, Doherty J, Fernandez-Luna JL, Real PJ, Tang HY, Sarma K. Yan Q, et al. Among authors: sarma k. Nat Commun. 2022 Jan 10;13(1):53. doi: 10.1038/s41467-021-27722-6. Nat Commun. 2022. PMID: 35013239 Free PMC article.

5

MapR: A Method for Identifying Native R-Loops Genome Wide.

Yan Q, Sarma K. Yan Q, et al. Among authors: sarma k. Curr Protoc Mol Biol. 2020 Mar;130(1):e113. doi: 10.1002/cpmb.113. Curr Protoc Mol Biol. 2020. PMID: 31943854 Free PMC article.

6

A nuclease- and bisulfite-based strategy captures strand-specific R-loops genome-wide.

Wulfridge P, Sarma K. Wulfridge P, et al. Among authors: sarma k. Elife. 2021 Feb 23;10:e65146. doi: 10.7554/eLife.65146. Elife. 2021. PMID: 33620319 Free PMC article.

7

ATRX histone binding and helicase activities have distinct roles in neuronal differentiation.

Bieluszewska A, Wulfridge P, Doherty J, Ren W, Sarma K. Bieluszewska A, et al. Among authors: sarma k. Nucleic Acids Res. 2022 Sep 9;50(16):9162-9174. doi: 10.1093/nar/gkac683. Nucleic Acids Res. 2022. PMID: 35998910 Free PMC article.

8

Mapping Native R-Loops Genome-wide Using a Targeted Nuclease Approach.

Yan Q, Shields EJ, Bonasio R, Sarma K. Yan Q, et al. Among authors: sarma k. Cell Rep. 2019 Oct 29;29(5):1369-1380.e5. doi: 10.1016/j.celrep.2019.09.052. Cell Rep. 2019. PMID: 31665646 Free PMC article.

9

Disruption of ATRX-RNA interactions uncovers roles in ATRX localization and PRC2 function.

Ren W, Medeiros N, Warneford-Thomson R, Wulfridge P, Yan Q, Bian J, Sidoli S, Garcia BA, Skordalakes E, Joyce E, Bonasio R, Sarma K. Ren W, et al. Among authors: sarma k. Nat Commun. 2020 May 6;11(1):2219. doi: 10.1038/s41467-020-15902-9. Nat Commun. 2020. PMID: 32376827 Free PMC article.

10

Targeting the IRE1α/XBP1s pathway suppresses CARM1-expressing ovarian cancer.

Lin J, Liu H, Fukumoto T, Zundell J, Yan Q, Tang CA, Wu S, Zhou W, Guo D, Karakashev S, Hu CA, Sarma K, Kossenkov AV, Zhang R. Lin J, et al. Among authors: sarma k. Nat Commun. 2021 Sep 7;12(1):5321. doi: 10.1038/s41467-021-25684-3. Nat Commun. 2021. PMID: 34493732 Free PMC article.

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