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Interference With the AMPKα/mTOR/NLRP3 Signaling and the IL-23/IL-17 Axis Effectively Protects Against the Dextran Sulfate Sodium Intoxication in Rats: A New Paradigm in Empagliflozin and Metformin Reprofiling for the Management of Ulcerative Colitis.
Youssef ME, Abd El-Fattah EE, Abdelhamid AM, Eissa H, El-Ahwany E, Amin NA, Hetta HF, Mahmoud MH, Batiha GE, Gobba N, Ahmed Gaafar AG, Saber S. Youssef ME, et al. Among authors: saber s. Front Pharmacol. 2021 Aug 16;12:719984. doi: 10.3389/fphar.2021.719984. eCollection 2021. Front Pharmacol. 2021. PMID: 34489707 Free PMC article.
Blunting p38 MAPKα and ERK1/2 activities by empagliflozin enhances the antifibrotic effect of metformin and augments its AMPK-induced NF-κB inactivation in mice intoxicated with carbon tetrachloride.
Abdelhamid AM, Youssef ME, Abd El-Fattah EE, Gobba NA, Gaafar AGA, Girgis S, Shata A, Hafez AM, El-Ahwany E, Amin NA, Shahien MA, Abd-Eldayem MA, Abou-Elrous M, Saber S. Abdelhamid AM, et al. Among authors: saber s. Life Sci. 2021 Dec 1;286:120070. doi: 10.1016/j.lfs.2021.120070. Epub 2021 Oct 21. Life Sci. 2021. PMID: 34688695
Empagliflozin adjunct with metformin for the inhibition of hepatocellular carcinoma progression: Emerging approach for new application.
Abdelhamid AM, Saber S, Youssef ME, Gaafar AGA, Eissa H, Abd-Eldayem MA, Alqarni M, Batiha GE, Obaidullah AJ, Shahien MA, El-Ahwany E, Amin NA, Etman MA, Kaddah MMY, Abd El-Fattah EE. Abdelhamid AM, et al. Among authors: saber s. Biomed Pharmacother. 2022 Jan;145:112455. doi: 10.1016/j.biopha.2021.112455. Epub 2021 Nov 26. Biomed Pharmacother. 2022. PMID: 34844106 Free article.
The dynamic interplay between AMPK/NFκB signaling and NLRP3 is a new therapeutic target in inflammation: Emerging role of dapagliflozin in overcoming lipopolysaccharide-mediated lung injury.
Abd El-Fattah EE, Saber S, Mourad AAE, El-Ahwany E, Amin NA, Cavalu S, Yahya G, Saad AS, Alsharidah M, Shata A, Sami HM, Kaddah MMY, Ghanim AMH. Abd El-Fattah EE, et al. Among authors: saber s. Biomed Pharmacother. 2022 Mar;147:112628. doi: 10.1016/j.biopha.2022.112628. Epub 2022 Jan 12. Biomed Pharmacother. 2022. PMID: 35032769 Free article.
AKT-AMPKα-mTOR-dependent HIF-1α Activation is a New Therapeutic Target for Cancer Treatment: A Novel Approach to Repositioning the Antidiabetic Drug Sitagliptin for the Management of Hepatocellular Carcinoma.
Abd El-Fattah EE, Saber S, Youssef ME, Eissa H, El-Ahwany E, Amin NA, Alqarni M, Batiha GE, Obaidullah AJ, Kaddah MMY, Ahmed Gaafar AG, Mourad AAE, Mostafa-Hedeab G, Abdelhamid AM. Abd El-Fattah EE, et al. Among authors: saber s. Front Pharmacol. 2022 Jan 12;12:720173. doi: 10.3389/fphar.2021.720173. eCollection 2021. Front Pharmacol. 2022. PMID: 35095479 Free PMC article.
Coomassie brilliant blue G-250 dye attenuates bleomycin-induced lung fibrosis by regulating the NF-κB and NLRP3 crosstalk: A novel approach for filling an unmet medical need.
Zohny MH, Cavalu S, Youssef ME, Kaddah MMY, Mourad AAE, Gaafar AGA, El-Ahwany E, Amin NA, Arakeep HM, Shata A, Saleh S, Hafez MM, Elazab ST, Abdelhady R, El Shahat RM, Yahya G, Saber S. Zohny MH, et al. Among authors: saber s. Biomed Pharmacother. 2022 Apr;148:112723. doi: 10.1016/j.biopha.2022.112723. Epub 2022 Feb 21. Biomed Pharmacother. 2022. PMID: 35202914 Free article.
Nifuroxazide-loaded cubosomes exhibit an advancement in pulmonary delivery and attenuate bleomycin-induced lung fibrosis by regulating the STAT3 and NF-κB signaling: A new challenge for unmet therapeutic needs.
Saber S, Nasr M, Kaddah MMY, Mostafa-Hedeab G, Cavalu S, Mourad AAE, Gaafar AGA, Zaghlool SS, Saleh S, Hafez MM, Girgis S, Elgharabawy RM, Nader K, Alsharidah M, Batiha GE, El-Ahwany E, Amin NA, Elagamy HI, Shata A, Nader R, Khodir AE. Saber S, et al. Biomed Pharmacother. 2022 Apr;148:112731. doi: 10.1016/j.biopha.2022.112731. Epub 2022 Feb 24. Biomed Pharmacother. 2022. PMID: 35220029 Free article.
Combination of Vitamin C and Curcumin Safeguards Against Methotrexate-Induced Acute Liver Injury in Mice by Synergistic Antioxidant Effects.
Hasan Khudhair D, Al-Gareeb AI, Al-Kuraishy HM, El-Kadem AH, Elekhnawy E, Negm WA, Saber S, Cavalu S, Tirla A, Alotaibi SS, Batiha GE. Hasan Khudhair D, et al. Among authors: saber s. Front Med (Lausanne). 2022 Apr 14;9:866343. doi: 10.3389/fmed.2022.866343. eCollection 2022. Front Med (Lausanne). 2022. PMID: 35492324 Free PMC article.
285 results