Rowland M - Search Results

1

Bridging the efficacy-effectiveness gap: a regulator's perspective on addressing variability of drug response.

Eichler HG, Abadie E, Breckenridge A, Flamion B, Gustafsson LL, Leufkens H, Rowland M, Schneider CK, Bloechl-Daum B. Eichler HG, et al. Among authors: rowland m. Nat Rev Drug Discov. 2011 Jul 1;10(7):495-506. doi: 10.1038/nrd3501. Nat Rev Drug Discov. 2011. PMID: 21720406 Review.

2

Factors influencing non-approval of new drugs in Europe.

Putzeist M, Mantel-Teeuwisse AK, Aronsson B, Rowland M, Gispen-de Wied CC, Vamvakas S, Hoes AW, Leufkens HG, Eichler HG. Putzeist M, et al. Among authors: rowland m. Nat Rev Drug Discov. 2012 Dec;11(12):903-4. doi: 10.1038/nrd3894. Nat Rev Drug Discov. 2012. PMID: 23197028 No abstract available.

3

Proceedings: Alterations in the response to warfarin.

Breckenridge A, Orme M, Rowland M, Shearer M, Lewis RJ. Breckenridge A, et al. Among authors: rowland m. Acta Pharm Suec. 1974 Dec;11(6):652-3. Acta Pharm Suec. 1974. PMID: 1136804 No abstract available.

4

Phase 0/microdosing approaches: time for mainstream application in drug development?

Burt T, Young G, Lee W, Kusuhara H, Langer O, Rowland M, Sugiyama Y. Burt T, et al. Among authors: rowland m. Nat Rev Drug Discov. 2020 Nov;19(11):801-818. doi: 10.1038/s41573-020-0080-x. Epub 2020 Sep 8. Nat Rev Drug Discov. 2020. PMID: 32901140 Review.

5

Inter-relationship among individual vitamin K-dependent clotting factors at different levels of anticoagulation.

Chan E, Aarons L, Serlin M, Breckenridge A, Rowland M. Chan E, et al. Among authors: rowland m. Br J Clin Pharmacol. 1987 Nov;24(5):621-5. doi: 10.1111/j.1365-2125.1987.tb03221.x. Br J Clin Pharmacol. 1987. PMID: 3435692 Free PMC article.

6

Impact of target interactions on small-molecule drug disposition: an overlooked area.

van Waterschoot RAB, Parrott NJ, Olivares-Morales A, Lavé T, Rowland M, Smith DA. van Waterschoot RAB, et al. Among authors: rowland m. Nat Rev Drug Discov. 2018 Apr;17(4):299. doi: 10.1038/nrd.2018.26. Epub 2018 Feb 23. Nat Rev Drug Discov. 2018. PMID: 29472637 No abstract available.

7

Importance of target-mediated drug disposition for small molecules.

Smith DA, van Waterschoot RAB, Parrott NJ, Olivares-Morales A, Lavé T, Rowland M. Smith DA, et al. Among authors: rowland m. Drug Discov Today. 2018 Dec;23(12):2023-2030. doi: 10.1016/j.drudis.2018.06.010. Epub 2018 Jun 19. Drug Discov Today. 2018. PMID: 29928850 Review.

8

Warfarin-phenylbutazone interaction in man: a long term multiple dose study.

Schary WL, Lewis RJ, Rowland M. Schary WL, et al. Among authors: rowland m. Res Commun Chem Pathol Pharmacol. 1975 Apr;10(4):663-72. Res Commun Chem Pathol Pharmacol. 1975. PMID: 1153844

9

Microdosing and Other Phase 0 Clinical Trials: Facilitating Translation in Drug Development.

Burt T, Yoshida K, Lappin G, Vuong L, John C, de Wildt SN, Sugiyama Y, Rowland M. Burt T, et al. Among authors: rowland m. Clin Transl Sci. 2016 Apr;9(2):74-88. doi: 10.1111/cts.12390. Epub 2016 Mar 30. Clin Transl Sci. 2016. PMID: 26918865 Free PMC article. Review.

10

Intra-Target Microdosing (ITM): A Novel Drug Development Approach Aimed at Enabling Safer and Earlier Translation of Biological Insights Into Human Testing.

Burt T, Noveck RJ, MacLeod DB, Layton AT, Rowland M, Lappin G. Burt T, et al. Among authors: rowland m. Clin Transl Sci. 2017 Sep;10(5):337-350. doi: 10.1111/cts.12464. Epub 2017 Apr 18. Clin Transl Sci. 2017. PMID: 28419765 Free PMC article. Review. No abstract available.

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