Impact of target interactions on small-molecule drug disposition: an overlooked area
Nat Rev Drug Discov
.
2018 Apr;17(4):299.
doi: 10.1038/nrd.2018.26.
Epub 2018 Feb 23.
Authors
Robert A B van Waterschoot
1
,
Neil J Parrott
1
,
Andrés Olivares-Morales
1
,
Thierry Lavé
1
,
Malcolm Rowland
2
,
Dennis A Smith
3
Affiliations
1
Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, Switzerland.
2
Centre for Applied Pharmacokinetic Research, Manchester Pharmacy School, University of Manchester, Manchester, UK.
3
Department of Chemistry, University of Capetown, Capetown, South Africa.
PMID:
29472637
DOI:
10.1038/nrd.2018.26
No abstract available
Publication types
Comment
MeSH terms
Drug Delivery Systems*
Tissue Distribution