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Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism.
Johnson MO, Wolf MM, Madden MZ, Andrejeva G, Sugiura A, Contreras DC, Maseda D, Liberti MV, Paz K, Kishton RJ, Johnson ME, de Cubas AA, Wu P, Li G, Zhang Y, Newcomb DC, Wells AD, Restifo NP, Rathmell WK, Locasale JW, Davila ML, Blazar BR, Rathmell JC. Johnson MO, et al. Among authors: rathmell jc, rathmell wk. Cell. 2018 Dec 13;175(7):1780-1795.e19. doi: 10.1016/j.cell.2018.10.001. Epub 2018 Nov 1. Cell. 2018. PMID: 30392958 Free PMC article.
Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation.
Michalek RD, Gerriets VA, Nichols AG, Inoue M, Kazmin D, Chang CY, Dwyer MA, Nelson ER, Pollizzi KN, Ilkayeva O, Giguere V, Zuercher WJ, Powell JD, Shinohara ML, McDonnell DP, Rathmell JC. Michalek RD, et al. Among authors: rathmell jc. Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18348-53. doi: 10.1073/pnas.1108856108. Epub 2011 Oct 31. Proc Natl Acad Sci U S A. 2011. PMID: 22042850 Free PMC article.
Metabolic pathways in T cell fate and function.
Gerriets VA, Rathmell JC. Gerriets VA, et al. Among authors: rathmell jc. Trends Immunol. 2012 Apr;33(4):168-73. doi: 10.1016/j.it.2012.01.010. Epub 2012 Feb 17. Trends Immunol. 2012. PMID: 22342741 Free PMC article. Review.
HIF1α and HIF2α exert distinct nutrient preferences in renal cells.
Arreola A, Cowey CL, Coloff JL, Rathmell JC, Rathmell WK. Arreola A, et al. Among authors: rathmell jc, rathmell wk. PLoS One. 2014 May 30;9(5):e98705. doi: 10.1371/journal.pone.0098705. eCollection 2014. PLoS One. 2014. PMID: 24879016 Free PMC article.
Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation.
Gerriets VA, Kishton RJ, Nichols AG, Macintyre AN, Inoue M, Ilkayeva O, Winter PS, Liu X, Priyadharshini B, Slawinska ME, Haeberli L, Huck C, Turka LA, Wood KC, Hale LP, Smith PA, Schneider MA, MacIver NJ, Locasale JW, Newgard CB, Shinohara ML, Rathmell JC. Gerriets VA, et al. Among authors: rathmell jc. J Clin Invest. 2015 Jan;125(1):194-207. doi: 10.1172/JCI76012. Epub 2014 Dec 1. J Clin Invest. 2015. PMID: 25437876 Free PMC article.
223 results