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Synthesis of Novel Nicotinic Ligands with Multimodal Action: Targeting Acetylcholine α4β2, Dopamine and Serotonin Transporters.
González-Gutiérrez JP, Pessoa-Mahana HA, Iturriaga-Vásquez PE, Reyes-Parada MI, Guerra-Díaz NE, Hodar-Salazar M, Viscarra F, Paillali P, Núñez-Vivanco G, Lorca-Carvajal MA, Mella-Raipán J, Zúñiga MC. González-Gutiérrez JP, et al. Among authors: pessoa mahana ha. Molecules. 2019 Oct 22;24(20):3808. doi: 10.3390/molecules24203808. Molecules. 2019. PMID: 31652614 Free PMC article.
Synthesis, docking and pharmacological evaluation of novel homo- and hetero-bis 3-piperazinylpropylindole derivatives at SERT and 5-HT1A receptor.
Pessoa-Mahana H, González-Lira C, Fierro A, Zapata-Torres G, Pessoa-Mahana CD, Ortiz-Severin J, Iturriaga-Vásquez P, Reyes-Parada M, Silva-Matus P, Saitz-Barría C, Araya-Maturana R. Pessoa-Mahana H, et al. Bioorg Med Chem. 2013 Dec 15;21(24):7604-11. doi: 10.1016/j.bmc.2013.10.036. Epub 2013 Nov 6. Bioorg Med Chem. 2013. PMID: 24262884
Design, synthesis, biological evaluation and binding mode modeling of benzimidazole derivatives targeting the cannabinoid receptor type 1.
Espinosa-Bustos C, Lagos CF, Romero-Parra J, Zárate AM, Mella-Raipán J, Pessoa-Mahana H, Recabarren-Gajardo G, Iturriaga-Vásquez P, Tapia RA, Pessoa-Mahana CD. Espinosa-Bustos C, et al. Arch Pharm (Weinheim). 2015 Feb;348(2):81-8. doi: 10.1002/ardp.201400201. Epub 2015 Jan 13. Arch Pharm (Weinheim). 2015. PMID: 25641513
Synthesis, binding assays, cytotoxic activity and docking studies of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor.
Romero-Parra J, Mella-Raipán J, Palmieri V, Allarà M, Torres MJ, Pessoa-Mahana H, Iturriaga-Vásquez P, Escobar R, Faúndez M, Di Marzo V, Pessoa-Mahana CD. Romero-Parra J, et al. Eur J Med Chem. 2016 Nov 29;124:17-35. doi: 10.1016/j.ejmech.2016.08.005. Epub 2016 Aug 5. Eur J Med Chem. 2016. PMID: 27560280
Synthesis and Docking of Novel 3-Indolylpropyl Derivatives as New Polypharmacological Agents Displaying Affinity for 5-HT1A R/SERT.
Pessoa-Mahana H, Silva-Matus P, Pessoa-Mahana CD, Chung H, Iturriaga-Vásquez P, Quiroz G, Möller-Acuña P, Zapata-Torres G, Saitz-Barría C, Araya-Maturana R, Reyes-Parada M. Pessoa-Mahana H, et al. Arch Pharm (Weinheim). 2017 Jan;350(1). doi: 10.1002/ardp.201600271. Epub 2016 Dec 16. Arch Pharm (Weinheim). 2017. PMID: 27981607
Synthesis and biological evaluation of potential acetylcholinesterase inhibitors based on a benzoxazine core.
Méndez-Rojas C, Quiroz G, Faúndez M, Gallardo-Garrido C, Pessoa-Mahana CD, Chung H, Gallardo-Toledo E, Saitz-Barría C, Araya-Maturana R, Kogan MJ, Zúñiga-López MC, Iturriaga-Vásquez P, Valenzuela-Gutiérrez C, Pessoa-Mahana H. Méndez-Rojas C, et al. Arch Pharm (Weinheim). 2018 May;351(5):e1800024. doi: 10.1002/ardp.201800024. Epub 2018 Apr 3. Arch Pharm (Weinheim). 2018. PMID: 29611620
31 results