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Tissue fluidification promotes a cGAS-STING cytosolic DNA response in invasive breast cancer.
Frittoli E, Palamidessi A, Iannelli F, Zanardi F, Villa S, Barzaghi L, Abdo H, Cancila V, Beznoussenko GV, Della Chiara G, Pagani M, Malinverno C, Bhattacharya D, Pisati F, Yu W, Galimberti V, Bonizzi G, Martini E, Mironov AA, Gioia U, Ascione F, Li Q, Havas K, Magni S, Lavagnino Z, Pennacchio FA, Maiuri P, Caponi S, Mattarelli M, Martino S, d'Adda di Fagagna F, Rossi C, Lucioni M, Tancredi R, Pedrazzoli P, Vecchione A, Petrini C, Ferrari F, Lanzuolo C, Bertalot G, Nader G, Foiani M, Piel M, Cerbino R, Giavazzi F, Tripodo C, Scita G. Frittoli E, et al. Among authors: pennacchio fa. Nat Mater. 2023 May;22(5):644-655. doi: 10.1038/s41563-022-01431-x. Epub 2022 Dec 29. Nat Mater. 2023. PMID: 36581770 Free PMC article.
The transcription factor PREP1(PKNOX1) regulates nuclear stiffness, the expression of LINC complex proteins and mechanotransduction.
Purushothaman D, Bianchi LF, Penkov D, Poli A, Li Q, Vermezovic J, Pramotton FM, Choudhary R, Pennacchio FA, Sommariva E, Foiani M, Gauthier N, Maiuri P, Blasi F. Purushothaman D, et al. Among authors: pennacchio fa. Commun Biol. 2022 May 12;5(1):456. doi: 10.1038/s42003-022-03406-9. Commun Biol. 2022. PMID: 35550602 Free PMC article.
Author Correction: Tissue fluidification promotes a cGAS-STING cytosolic DNA response in invasive breast cancer.
Frittoli E, Palamidessi A, Iannelli F, Zanardi F, Villa S, Barzaghi L, Abdo H, Cancila V, Beznoussenko GV, Della Chiara G, Pagani M, Malinverno C, Bhattacharya D, Pisati F, Yu W, Galimberti V, Bonizzi G, Martini E, Mironov AA, Gioia U, Ascione F, Li Q, Havas K, Magni S, Lavagnino Z, Pennacchio FA, Maiuri P, Caponi S, Mattarelli M, Martino S, d'Adda di Fagagna F, Rossi C, Lucioni M, Tancredi R, Pedrazzoli P, Vecchione A, Petrini C, Ferrari F, Lanzuolo C, Bertalot G, Nader G, Foiani M, Piel M, Cerbino R, Giavazzi F, Tripodo C, Scita G. Frittoli E, et al. Among authors: pennacchio fa. Nat Mater. 2023 Mar;22(3):400. doi: 10.1038/s41563-023-01479-3. Nat Mater. 2023. PMID: 36702890 Free PMC article. No abstract available.
PIP4K2B is mechanoresponsive and controls heterochromatin-driven nuclear softening through UHRF1.
Poli A, Pennacchio FA, Ghisleni A, di Gennaro M, Lecacheur M, Nastały P, Crestani M, Pramotton FM, Iannelli F, Beznusenko G, Mironov AA, Panzetta V, Fusco S, Sheth B, Poulikakos D, Ferrari A, Gauthier N, Netti PA, Divecha N, Maiuri P. Poli A, et al. Among authors: pennacchio fa. Nat Commun. 2023 Mar 14;14(1):1432. doi: 10.1038/s41467-023-37064-0. Nat Commun. 2023. PMID: 36918565 Free PMC article.
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