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Genetically Defined Syngeneic Mouse Models of Ovarian Cancer as Tools for the Discovery of Combination Immunotherapy.
Iyer S, Zhang S, Yucel S, Horn H, Smith SG, Reinhardt F, Hoefsmit E, Assatova B, Casado J, Meinsohn MC, Barrasa MI, Bell GW, Pérez-Villatoro F, Huhtinen K, Hynninen J, Oikkonen J, Galhenage PM, Pathania S, Hammond PT, Neel BG, Farkkila A, Pépin D, Weinberg RA. Iyer S, et al. Among authors: pathania s. Cancer Discov. 2021 Feb;11(2):384-407. doi: 10.1158/2159-8290.CD-20-0818. Epub 2020 Nov 6. Cancer Discov. 2021. PMID: 33158843 Free PMC article.
MAPK Pathway Suppression Unmasks Latent DNA Repair Defects and Confers a Chemical Synthetic Vulnerability in BRAF-, NRAS-, and NF1-Mutant Melanomas.
Maertens O, Kuzmickas R, Manchester HE, Emerson CE, Gavin AG, Guild CJ, Wong TC, De Raedt T, Bowman-Colin C, Hatchi E, Garraway LA, Flaherty KT, Pathania S, Elledge SJ, Cichowski K. Maertens O, et al. Among authors: pathania s. Cancer Discov. 2019 Apr;9(4):526-545. doi: 10.1158/2159-8290.CD-18-0879. Epub 2019 Feb 1. Cancer Discov. 2019. PMID: 30709805 Free PMC article.
BRCA1/Trp53 heterozygosity and replication stress drive esophageal cancer development in a mouse model.
He Y, Rivera J, Diossy M, Duan H, Bowman-Colin C, Reed R, Jennings R, Novak J, Tran SV, Cohen EF, Szuts D, Giobbie-Hurder A, Bronson RT, Bass AJ, Signoretti S, Szallasi Z, Livingston DM, Pathania S. He Y, et al. Among authors: pathania s. Proc Natl Acad Sci U S A. 2021 Oct 12;118(41):e2108421118. doi: 10.1073/pnas.2108421118. Proc Natl Acad Sci U S A. 2021. PMID: 34607954 Free PMC article.
RPA, RFWD3 and BRCA2 at stalled forks: a balancing act.
Duan H, Pathania S. Duan H, et al. Among authors: pathania s. Mol Cell Oncol. 2020 Aug 23;7(6):1801089. doi: 10.1080/23723556.2020.1801089. eCollection 2020. Mol Cell Oncol. 2020. PMID: 33241105 Free PMC article.
118 results