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Wnt dose escalation during the exit from pluripotency identifies tranilast as a regulator of cardiac mesoderm.
Wu Z, Shen S, Mizikovsky D, Cao Y, Naval-Sanchez M, Tan SZ, Alvarez YD, Sun Y, Chen X, Zhao Q, Kim D, Yang P, Hill TA, Jones A, Fairlie DP, Pébay A, Hewitt AW, Tam PPL, White MD, Nefzger CM, Palpant NJ. Wu Z, et al. Among authors: palpant nj. Dev Cell. 2024 Mar 25;59(6):705-722.e8. doi: 10.1016/j.devcel.2024.01.019. Epub 2024 Feb 13. Dev Cell. 2024. PMID: 38354738
Acid-sensing ion channel 1a blockade reduces myocardial injury in rodent models of myocardial infarction.
Redd MA, Yoshikawa Y, Khan N, Waqar M, Saez NJ, Outhwaite JE, Russell JS, Hanna AD, Chiu HS, Er SY, Butcher NJ, Mardon K, Fraser JF, Smythe ML, Rash LD, Thomas WG, King GF, Reichelt ME, Palpant NJ. Redd MA, et al. Among authors: palpant nj. Eur Heart J. 2024 May 7;45(17):1571-1574. doi: 10.1093/eurheartj/ehad793. Eur Heart J. 2024. PMID: 38095341 No abstract available.
HOPX-associated molecular programs control cardiomyocyte cell states underpinning cardiac structure and function.
Friedman CE, Cheetham SW, Negi S, Mills RJ, Ogawa M, Redd MA, Chiu HS, Shen S, Sun Y, Mizikovsky D, Bouveret R, Chen X, Voges HK, Paterson S, De Angelis JE, Andersen SB, Cao Y, Wu Y, Jafrani YMA, Yoon S, Faulkner GJ, Smith KA, Porrello E, Harvey RP, Hogan BM, Nguyen Q, Zeng J, Kikuchi K, Hudson JE, Palpant NJ. Friedman CE, et al. Among authors: palpant nj. Dev Cell. 2024 Jan 8;59(1):91-107.e6. doi: 10.1016/j.devcel.2023.11.012. Epub 2023 Dec 12. Dev Cell. 2024. PMID: 38091997
PDGF-AB Reduces Myofibroblast Differentiation Without Increasing Proliferation After Myocardial Infarction.
Hume RD, Deshmukh T, Doan T, Shim WJ, Kanagalingam S, Tallapragada V, Rashid F, Marcuello M, Blessing D, Selvakumar D, Raguram K, Pathan F, Graham D, Ounzain S, Kizana E, Harvey RP, Palpant NJ, Chong JJH. Hume RD, et al. Among authors: palpant nj. JACC Basic Transl Sci. 2023 Mar 1;8(6):658-674. doi: 10.1016/j.jacbts.2022.11.006. eCollection 2023 Jun. JACC Basic Transl Sci. 2023. PMID: 37426530 Free PMC article.
A village in a dish model system for population-scale hiPSC studies.
Neavin DR, Steinmann AM, Farbehi N, Chiu HS, Daniszewski MS, Arora H, Bermudez Y, Moutinho C, Chan CL, Bax M, Tyebally M, Gnanasambandapillai V, Lam CE, Nguyen U, Hernández D, Lidgerwood GE, Graham RM, Hewitt AW, Pébay A, Palpant NJ, Powell JE. Neavin DR, et al. Among authors: palpant nj. Nat Commun. 2023 Jun 9;14(1):3240. doi: 10.1038/s41467-023-38704-1. Nat Commun. 2023. PMID: 37296104 Free PMC article.
Vascular cells improve functionality of human cardiac organoids.
Voges HK, Foster SR, Reynolds L, Parker BL, Devilée L, Quaife-Ryan GA, Fortuna PRJ, Mathieson E, Fitzsimmons R, Lor M, Batho C, Reid J, Pocock M, Friedman CE, Mizikovsky D, Francois M, Palpant NJ, Needham EJ, Peralta M, Monte-Nieto GD, Jones LK, Smyth IM, Mehdiabadi NR, Bolk F, Janbandhu V, Yao E, Harvey RP, Chong JJH, Elliott DA, Stanley EG, Wiszniak S, Schwarz Q, James DE, Mills RJ, Porrello ER, Hudson JE. Voges HK, et al. Among authors: palpant nj. Cell Rep. 2023 May 30;42(5):112322. doi: 10.1016/j.celrep.2023.112322. Epub 2023 Apr 26. Cell Rep. 2023. PMID: 37105170 Free article.
The ins and outs of cellular pH during cardiac ischemia.
Cao Y, Palpant NJ. Cao Y, et al. Among authors: palpant nj. J Mol Cell Cardiol. 2023 Jan;174:133-134. doi: 10.1016/j.yjmcc.2022.12.004. Epub 2022 Dec 26. J Mol Cell Cardiol. 2023. PMID: 36581136 No abstract available.
55 results