Acid-sensing ion channel 1a blockade reduces myocardial injury in rodent models of myocardial infarction

Eur Heart J. 2023 Dec 14:ehad793. doi: 10.1093/eurheartj/ehad793. Online ahead of print.

Meredith A Redd^{1

2}, Yusuke Yoshikawa³, Nemat Khan³, Maleeha Waqar³, Natalie J Saez^{1

4

5}, Jennifer E Outhwaite^{1

3}, Jake S Russell³, Amy D Hanna¹, Han S Chiu^{1

5}, Sing Yan Er¹, Neville J Butcher³, Karine Mardon⁶, John F Fraser², Mark L Smythe⁵, Lachlan D Rash³, Walter G Thomas³, Glenn F King^{1

4

5}, Melissa E Reichelt³, Nathan J Palpant^{1

5}

¹ Institute for Molecular Bioscience, University of Queensland, 306 Carmody Road, St.Lucia, QLD 4072, Australia.
² Critical Care Research Group, The Prince Charles Hospital Northside Clinical Unit and Faculty of Medicine, University of Queensland, Australia.
³ School of Biomedical Sciences, University of Queensland, Australia.
⁴ Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, University of Queensland, Australia.
⁵ Infensa Bioscience Pty Ltd, Brisbane, QLD 4101, Australia.
⁶ Center for Advanced Imaging, University of Queensland, Australia.

No abstract available

Keywords: Cardioprotection; Hi1a; Ischemia-reperfusion injury.

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