Nomura DK - Search Results

1

Discovery of a Functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC.

Boike L, Cioffi AG, Majewski FC, Co J, Henning NJ, Jones MD, Liu G, McKenna JM, Tallarico JA, Schirle M, Nomura DK. Boike L, et al. Among authors: nomura dk. Cell Chem Biol. 2021 Jan 21;28(1):4-13.e17. doi: 10.1016/j.chembiol.2020.09.001. Epub 2020 Sep 22. Cell Chem Biol. 2021. PMID: 32966806 Free PMC article.

2

Discovery of Inhibitors for the Ether Lipid-Generating Enzyme AGPS as Anti-Cancer Agents.

Piano V, Benjamin DI, Valente S, Nenci S, Marrocco B, Mai A, Aliverti A, Nomura DK, Mattevi A. Piano V, et al. Among authors: nomura dk. ACS Chem Biol. 2015 Nov 20;10(11):2589-97. doi: 10.1021/acschembio.5b00466. Epub 2015 Sep 4. ACS Chem Biol. 2015. PMID: 26322624 Free PMC article.

3

GSTP1 Is a Driver of Triple-Negative Breast Cancer Cell Metabolism and Pathogenicity.

Louie SM, Grossman EA, Crawford LA, Ding L, Camarda R, Huffman TR, Miyamoto DK, Goga A, Weerapana E, Nomura DK. Louie SM, et al. Among authors: nomura dk. Cell Chem Biol. 2016 May 19;23(5):567-578. doi: 10.1016/j.chembiol.2016.03.017. Epub 2016 May 12. Cell Chem Biol. 2016. PMID: 27185638 Free PMC article.

4

Mapping Proteome-wide Targets of Glyphosate in Mice.

Ford B, Bateman LA, Gutierrez-Palominos L, Park R, Nomura DK. Ford B, et al. Among authors: nomura dk. Cell Chem Biol. 2017 Feb 16;24(2):133-140. doi: 10.1016/j.chembiol.2016.12.013. Epub 2017 Jan 26. Cell Chem Biol. 2017. PMID: 28132892 Free article.

5

Chemoproteomic Screening of Covalent Ligands Reveals UBA5 As a Novel Pancreatic Cancer Target.

Roberts AM, Miyamoto DK, Huffman TR, Bateman LA, Ives AN, Akopian D, Heslin MJ, Contreras CM, Rape M, Skibola CF, Nomura DK. Roberts AM, et al. Among authors: nomura dk. ACS Chem Biol. 2017 Apr 21;12(4):899-904. doi: 10.1021/acschembio.7b00020. Epub 2017 Feb 15. ACS Chem Biol. 2017. PMID: 28186401

6

MYC-driven inhibition of the glutamate-cysteine ligase promotes glutathione depletion in liver cancer.

Anderton B, Camarda R, Balakrishnan S, Balakrishnan A, Kohnz RA, Lim L, Evason KJ, Momcilovic O, Kruttwig K, Huang Q, Xu G, Nomura DK, Goga A. Anderton B, et al. Among authors: nomura dk. EMBO Rep. 2017 Apr;18(4):569-585. doi: 10.15252/embr.201643068. Epub 2017 Feb 20. EMBO Rep. 2017. PMID: 28219903 Free PMC article.

7

Argininosuccinate Synthase 1 is a Metabolic Regulator of Colorectal Cancer Pathogenicity.

Bateman LA, Ku WM, Heslin MJ, Contreras CM, Skibola CF, Nomura DK. Bateman LA, et al. Among authors: nomura dk. ACS Chem Biol. 2017 Apr 21;12(4):905-911. doi: 10.1021/acschembio.6b01158. Epub 2017 Mar 1. ACS Chem Biol. 2017. PMID: 28229591

8

Chemoproteomics-enabled covalent ligand screen reveals a cysteine hotspot in reticulon 4 that impairs ER morphology and cancer pathogenicity.

Bateman LA, Nguyen TB, Roberts AM, Miyamoto DK, Ku WM, Huffman TR, Petri Y, Heslin MJ, Contreras CM, Skibola CF, Olzmann JA, Nomura DK. Bateman LA, et al. Among authors: nomura dk. Chem Commun (Camb). 2017 Jun 29;53(53):7234-7237. doi: 10.1039/c7cc01480e. Chem Commun (Camb). 2017. PMID: 28352901 Free PMC article.

9

Chemoproteomics-Enabled Covalent Ligand Screening Reveals a Thioredoxin-Caspase 3 Interaction Disruptor That Impairs Breast Cancer Pathogenicity.

Anderson KE, To M, Olzmann JA, Nomura DK. Anderson KE, et al. Among authors: nomura dk. ACS Chem Biol. 2017 Oct 20;12(10):2522-2528. doi: 10.1021/acschembio.7b00711. Epub 2017 Sep 13. ACS Chem Biol. 2017. PMID: 28892616 Free PMC article.

10

Covalent Ligand Discovery against Druggable Hotspots Targeted by Anti-cancer Natural Products.

Grossman EA, Ward CC, Spradlin JN, Bateman LA, Huffman TR, Miyamoto DK, Kleinman JI, Nomura DK. Grossman EA, et al. Among authors: nomura dk. Cell Chem Biol. 2017 Nov 16;24(11):1368-1376.e4. doi: 10.1016/j.chembiol.2017.08.013. Epub 2017 Sep 14. Cell Chem Biol. 2017. PMID: 28919038 Free PMC article.

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