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CRISPR-based engineering of RNA viruses.
Nemudryi A, Nemudraia A, Nichols JE, Scherffius AM, Zahl T, Wiedenheft B. Nemudryi A, et al. Sci Adv. 2023 Sep 15;9(37):eadj8277. doi: 10.1126/sciadv.adj8277. Epub 2023 Sep 13. Sci Adv. 2023. PMID: 37703376 Free PMC article.
Sequence-specific capture and concentration of viral RNA by type III CRISPR system enhances diagnostic.
Nemudraia A, Nemudryi A, Buyukyoruk M, Scherffius AM, Zahl T, Wiegand T, Pandey S, Nichols JE, Hall LN, McVey A, Lee HH, Wilkinson RA, Snyder LR, Jones JD, Koutmou KS, Santiago-Frangos A, Wiedenheft B. Nemudraia A, et al. Among authors: nemudryi a. Nat Commun. 2022 Dec 15;13(1):7762. doi: 10.1038/s41467-022-35445-5. Nat Commun. 2022. PMID: 36522348 Free PMC article.
CRISPR RNA-guided autonomous delivery of Cas9.
Wilkinson RA, Martin C, Nemudryi AA, Wiedenheft B. Wilkinson RA, et al. Among authors: nemudryi aa. Nat Struct Mol Biol. 2019 Jan;26(1):14-24. doi: 10.1038/s41594-018-0173-y. Epub 2018 Dec 31. Nat Struct Mol Biol. 2019. PMID: 30598555 Free PMC article. Review.
Intrinsic signal amplification by type III CRISPR-Cas systems provides a sequence-specific SARS-CoV-2 diagnostic.
Santiago-Frangos A, Hall LN, Nemudraia A, Nemudryi A, Krishna P, Wiegand T, Wilkinson RA, Snyder DT, Hedges JF, Cicha C, Lee HH, Graham A, Jutila MA, Taylor MP, Wiedenheft B. Santiago-Frangos A, et al. Among authors: nemudryi a. Cell Rep Med. 2021 Jun 15;2(6):100319. doi: 10.1016/j.xcrm.2021.100319. Epub 2021 May 27. Cell Rep Med. 2021. PMID: 34075364 Free PMC article.
A viral "codebreaker" intercepts a host alarm.
Nemudryi A, Nemudraia A, Wiegand T, Sternberg SH, Wiedenheft B. Nemudryi A, et al. Cell Host Microbe. 2022 Dec 14;30(12):1647-1648. doi: 10.1016/j.chom.2022.11.005. Cell Host Microbe. 2022. PMID: 36521436 Free article.
20 results