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IDH3γ functions as a redox switch regulating mitochondrial energy metabolism and contractility in the heart.
Nanadikar MS, Vergel Leon AM, Guo J, van Belle GJ, Jatho A, Philip ES, Brandner AF, Böckmann RA, Shi R, Zieseniss A, Siemssen CM, Dettmer K, Brodesser S, Schmidtendorf M, Lee J, Wu H, Furdui CM, Brandenburg S, Burgoyne JR, Bogeski I, Riemer J, Chowdhury A, Rehling P, Bruegmann T, Belousov VV, Katschinski DM. Nanadikar MS, et al. Nat Commun. 2023 Apr 14;14(1):2123. doi: 10.1038/s41467-023-37744-x. Nat Commun. 2023. PMID: 37055412 Free PMC article.
O2 affects mitochondrial functionality ex vivo.
Nanadikar MS, Vergel Leon AM, Borowik S, Hillemann A, Zieseniss A, Belousov VV, Bogeski I, Rehling P, Dudek J, Katschinski DM. Nanadikar MS, et al. Redox Biol. 2019 Apr;22:101152. doi: 10.1016/j.redox.2019.101152. Epub 2019 Feb 23. Redox Biol. 2019. PMID: 30825773 Free PMC article.
Redox Imaging Using Cardiac Myocyte-Specific Transgenic Biosensor Mice.
Swain L, Kesemeyer A, Meyer-Roxlau S, Vettel C, Zieseniss A, Güntsch A, Jatho A, Becker A, Nanadikar MS, Morgan B, Dennerlein S, Shah AM, El-Armouche A, Nikolaev VO, Katschinski DM. Swain L, et al. Among authors: nanadikar ms. Circ Res. 2016 Oct 14;119(9):1004-1016. doi: 10.1161/CIRCRESAHA.116.309551. Epub 2016 Aug 23. Circ Res. 2016. PMID: 27553648
MCU controls melanoma progression through a redox-controlled phenotype switch.
Stejerean-Todoran I, Zimmermann K, Gibhardt CS, Vultur A, Ickes C, Shannan B, Bonilla Del Rio Z, Wölling A, Cappello S, Sung HM, Shumanska M, Zhang X, Nanadikar M, Latif MU, Wittek A, Lange F, Waters A, Brafford P, Wilting J, Urlaub H, Katschinski DM, Rehling P, Lenz C, Jakobs S, Ellenrieder V, Roesch A, Schön MP, Herlyn M, Stanisz H, Bogeski I. Stejerean-Todoran I, et al. EMBO Rep. 2022 Nov 7;23(11):e54746. doi: 10.15252/embr.202254746. Epub 2022 Sep 26. EMBO Rep. 2022. PMID: 36156348 Free PMC article.