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Physiological processes underlying organ injury in alcohol abuse.
Souza-Smith FM, Lang CH, Nagy LE, Bailey SM, Parsons LH, Murray GJ. Souza-Smith FM, et al. Among authors: nagy le. Am J Physiol Endocrinol Metab. 2016 Sep 1;311(3):E605-19. doi: 10.1152/ajpendo.00270.2016. Epub 2016 Jul 19. Am J Physiol Endocrinol Metab. 2016. PMID: 27436613 Free PMC article. Review.
Acute and chronic alcohol abuse modulate immunity.
Brown LA, Cook RT, Jerrells TR, Kolls JK, Nagy LE, Szabo G, Wands JR, Kovacs EJ. Brown LA, et al. Among authors: nagy le. Alcohol Clin Exp Res. 2006 Sep;30(9):1624-31. doi: 10.1111/j.1530-0277.2006.00195.x. Alcohol Clin Exp Res. 2006. PMID: 16930226
Alcohol-induced extracellular ASC specks perpetuate liver inflammation and damage in alcohol-associated hepatitis even after alcohol cessation.
de Carvalho Ribeiro M, Iracheta-Vellve A, Babuta M, Calenda CD, Copeland C, Zhuang Y, Lowe PP, Hawryluk D, Catalano D, Cho Y, Barton B, Dasarathy S, McClain C, McCullough AJ, Mitchell MC, Nagy LE, Radaeva S, Lien E, Golenbock DT, Szabo G. de Carvalho Ribeiro M, et al. Among authors: nagy le. Hepatology. 2023 Jul 1;78(1):225-242. doi: 10.1097/HEP.0000000000000298. Epub 2023 Mar 3. Hepatology. 2023. PMID: 36862512
A polygenic risk score for alcohol-associated cirrhosis among heavy drinkers with European ancestry.
Schwantes-An TH, Whitfield JB, Aithal GP, Atkinson SR, Bataller R, Botwin G, Chalasani NP, Cordell HJ, Daly AK, Darlay R, Day CP, Eyer F, Foroud T, Gawrieh S, Gleeson D, Goldman D, Haber PS, Jacquet JM, Lammert CS, Liang T, Liangpunsakul S, Masson S, Mathurin P, Moirand R, McQuillin A, Moreno C, Morgan MY, Mueller S, Müllhaupt B, Nagy LE, Nahon P, Nalpas B, Naveau S, Perney P, Pirmohamed M, Seitz HK, Soyka M, Stickel F, Thompson A, Thursz MR, Trépo E, Morgan TR, Seth D; GenomALC Consortium. Schwantes-An TH, et al. Among authors: nagy le. Hepatol Commun. 2024 May 10;8(6):e0431. doi: 10.1097/HC9.0000000000000431. eCollection 2024 Jun 1. Hepatol Commun. 2024. PMID: 38727677 Free PMC article.
Randomized trial of anakinra plus zinc vs. prednisone for severe alcohol-associated hepatitis.
Gawrieh S, Dasarathy S, Tu W, Kamath PS, Chalasani NP, McClain CJ, Bataller R, Szabo G, Tang Q, Radaeva S, Barton B, Nagy LE, Shah VH, Sanyal AJ, Mitchell MC; AlcHepNet Investigators. Gawrieh S, et al. Among authors: nagy le. J Hepatol. 2024 May;80(5):684-693. doi: 10.1016/j.jhep.2024.01.031. Epub 2024 Feb 10. J Hepatol. 2024. PMID: 38342441 Clinical Trial.
Membrane-bound O-acyltransferase 7 (MBOAT7) shapes lysosomal lipid homeostasis and function to control alcohol-associated liver injury.
Varadharajan V, Ramachandiran I, Massey WJ, Jain R, Banerjee R, Horak AJ, McMullen MR, Huang E, Bellar A, Lorkowski SW, Gulshan K, Helsley RN, James I, Pathak V, Dasarathy J, Welch N, Dasarathy S, Streem D, Reizes O, Allende DS, Smith JD, Simcox J, Nagy LE, Brown JM. Varadharajan V, et al. Among authors: nagy le. Elife. 2024 Apr 22;12:RP92243. doi: 10.7554/eLife.92243. Elife. 2024. PMID: 38648183 Free PMC article.
Proteomics identifies complement protein signatures in patients with alcohol-associated hepatitis.
Taiwo M, Huang E, Pathak V, Bellar A, Welch N, Dasarathy J, Streem D, McClain CJ, Mitchell MC, Barton BA, Szabo G, Dasarathy S; Alcohol Hepatitis Network (AlcHepNet) Consortium; Schaefer EA, Luther J, Day LZ, Ouyang X, Suyavaran A, Mehal WZ, Jacobs JM, Goodman RP, Rotroff DM, Nagy LE. Taiwo M, et al. Among authors: nagy le. JCI Insight. 2024 Apr 4;9(9):e174127. doi: 10.1172/jci.insight.174127. JCI Insight. 2024. PMID: 38573776 Free article.
209 results