Physiological processes underlying organ injury in alcohol abuse

Am J Physiol Endocrinol Metab. 2016 Sep 1;311(3):E605-19. doi: 10.1152/ajpendo.00270.2016. Epub 2016 Jul 19.

Abstract

This review summarizes the American Physiological Society (APS) Presidential Symposium 1 entitled "Physiological Processes Underlying Organ Injury in Alcohol Abuse" at the 2016 Experimental Biology meeting. The symposium was organized by Dr. Patricia Molina, past president of the APS, was held on April 3 at the Convention Center in San Diego, CA, and was funded by the National Institute on Alcohol Abuse and Alcoholism. The "Physiological Processes Underlying Organ Injury in Alcohol Abuse Symposium" assembled experts and leaders in the field and served as a platform to discuss and share knowledge on the latest developments and scientific advances on the mechanisms underlying organ injury in alcohol abuse. This symposium provided unique, interdisciplinary alcohol research, including several organs, liver, muscle, adipose, and brain, affected by excessive alcohol use.

Keywords: adipose tissue; alcohol; circadian clock; endocannabinoids; muscle atrophy.

Publication types

  • Review
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adipose Tissue / pathology
  • Alcoholism / pathology*
  • Animals
  • Brain / pathology
  • Endocannabinoids / metabolism
  • Humans
  • Liver / pathology
  • Muscular Atrophy / etiology
  • Muscular Atrophy / pathology

Substances

  • Endocannabinoids