Assessing the transferability and reproducibility of 3D in vitro liver models from primary human multi-cellular microtissues to cell-line based HepG2 spheroids.
Llewellyn SV, Kermanizadeh A, Ude V, Jacobsen NR, Conway GE, Shah UK, Niemeijer M, Moné MJ, van de Water B, Roy S, Moritz W, Stone V, Jenkins GJS, Doak SH.
Llewellyn SV, et al.
Toxicol In Vitro. 2022 Dec;85:105473. doi: 10.1016/j.tiv.2022.105473. Epub 2022 Sep 13.
Toxicol In Vitro. 2022.
PMID: 36108805
Free article.
To reduce, replace, and refine in vivo testing, there is increasing emphasis on the development of more physiologically relevant in vitro test systems to improve the reliability of non-animal-based methods for hazard assessment. ...
To reduce, replace, and refine in vivo testing, there is increasing emphasis on the development of more physiologically relevant in v …