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A Novel Combination Therapy Using Rosuvastatin and Lactobacillus Combats Dextran Sodium Sulfate-Induced Colitis in High-Fat Diet-Fed Rats by Targeting the TXNIP/NLRP3 Interaction and Influencing Gut Microbiome Composition.
Saber S, Abd El-Fattah EE, Yahya G, Gobba NA, Maghmomeh AO, Khodir AE, Mourad AAE, Saad AS, Mohammed HG, Nouh NA, Shata A, Amin NA, Abou El-Rous M, Girgis S, El-Ahwany E, Khalaf EM, El-Kott AF, El-Baz AM. Saber S, et al. Among authors: mourad aae. Pharmaceuticals (Basel). 2021 Apr 8;14(4):341. doi: 10.3390/ph14040341. Pharmaceuticals (Basel). 2021. PMID: 33917884 Free PMC article.
Albendazole-loaded cubosomes interrupt the ERK1/2-HIF-1α-p300/CREB axis in mice intoxicated with diethylnitrosamine: A new paradigm in drug repurposing for the inhibition of hepatocellular carcinoma progression.
Saber S, Nasr M, Saad AS, Mourad AAE, Gobba NA, Shata A, Hafez AM, Elsergany RN, Elagamy HI, El-Ahwany E, Amin NA, Girgis S, Elewa YHA, Mahmoud MH, Batiha GE, El-Rous MA, Kamal I, Kaddah MMY, Khodir AE. Saber S, et al. Among authors: mourad aae. Biomed Pharmacother. 2021 Oct;142:112029. doi: 10.1016/j.biopha.2021.112029. Epub 2021 Aug 17. Biomed Pharmacother. 2021. PMID: 34416629 Free article.
The dynamic interplay between AMPK/NFκB signaling and NLRP3 is a new therapeutic target in inflammation: Emerging role of dapagliflozin in overcoming lipopolysaccharide-mediated lung injury.
Abd El-Fattah EE, Saber S, Mourad AAE, El-Ahwany E, Amin NA, Cavalu S, Yahya G, Saad AS, Alsharidah M, Shata A, Sami HM, Kaddah MMY, Ghanim AMH. Abd El-Fattah EE, et al. Among authors: mourad aae. Biomed Pharmacother. 2022 Mar;147:112628. doi: 10.1016/j.biopha.2022.112628. Epub 2022 Jan 12. Biomed Pharmacother. 2022. PMID: 35032769 Free article.
AKT-AMPKα-mTOR-dependent HIF-1α Activation is a New Therapeutic Target for Cancer Treatment: A Novel Approach to Repositioning the Antidiabetic Drug Sitagliptin for the Management of Hepatocellular Carcinoma.
Abd El-Fattah EE, Saber S, Youssef ME, Eissa H, El-Ahwany E, Amin NA, Alqarni M, Batiha GE, Obaidullah AJ, Kaddah MMY, Ahmed Gaafar AG, Mourad AAE, Mostafa-Hedeab G, Abdelhamid AM. Abd El-Fattah EE, et al. Among authors: mourad aae. Front Pharmacol. 2022 Jan 12;12:720173. doi: 10.3389/fphar.2021.720173. eCollection 2021. Front Pharmacol. 2022. PMID: 35095479 Free PMC article.
Coomassie brilliant blue G-250 dye attenuates bleomycin-induced lung fibrosis by regulating the NF-κB and NLRP3 crosstalk: A novel approach for filling an unmet medical need.
Zohny MH, Cavalu S, Youssef ME, Kaddah MMY, Mourad AAE, Gaafar AGA, El-Ahwany E, Amin NA, Arakeep HM, Shata A, Saleh S, Hafez MM, Elazab ST, Abdelhady R, El Shahat RM, Yahya G, Saber S. Zohny MH, et al. Among authors: mourad aae. Biomed Pharmacother. 2022 Apr;148:112723. doi: 10.1016/j.biopha.2022.112723. Epub 2022 Feb 21. Biomed Pharmacother. 2022. PMID: 35202914 Free article.
Nifuroxazide-loaded cubosomes exhibit an advancement in pulmonary delivery and attenuate bleomycin-induced lung fibrosis by regulating the STAT3 and NF-κB signaling: A new challenge for unmet therapeutic needs.
Saber S, Nasr M, Kaddah MMY, Mostafa-Hedeab G, Cavalu S, Mourad AAE, Gaafar AGA, Zaghlool SS, Saleh S, Hafez MM, Girgis S, Elgharabawy RM, Nader K, Alsharidah M, Batiha GE, El-Ahwany E, Amin NA, Elagamy HI, Shata A, Nader R, Khodir AE. Saber S, et al. Among authors: mourad aae. Biomed Pharmacother. 2022 Apr;148:112731. doi: 10.1016/j.biopha.2022.112731. Epub 2022 Feb 24. Biomed Pharmacother. 2022. PMID: 35220029 Free article.
Ambroxol, a mucolytic agent, boosts HO-1, suppresses NF-κB, and decreases the susceptibility of the inflamed rat colon to apoptosis: A new treatment option for treating ulcerative colitis.
Cavalu S, Sharaf H, Saber S, Youssef ME, Abdelhamid AM, Mourad AAE, Ibrahim S, Allam S, Elgharabawy RM, El-Ahwany E, Amin NA, Shata A, Eldegla M, Atef M, Aboraya M, Mohamed M, Anz N, Elmotelb DA, Gabr F, Elzablawy D, Hamada M, Yehia A, Osama D, Mohammed OA. Cavalu S, et al. Among authors: mourad aae. FASEB J. 2022 Sep;36(9):e22496. doi: 10.1096/fj.202200749R. FASEB J. 2022. PMID: 35947115
Innovative challenge for the inhibition of hepatocellular carcinoma progression by combined targeting of HSP90 and STAT3/HIF-1α signaling.
Saber S, El-Fattah EEA, Abdelhamid AM, Mourad AAE, Hamouda MAM, Elrabat A, Zakaria S, Haleem AA, Mohamed SZ, Elgharabawy RM, Morsy NE, El Adle Khalaf N, Mohammed OA, El-Bahouty WB, Mostafa SA, Abdelhady R, Galal O, ElSaid ZH, Yahya G, Shata A, Youssef ME. Saber S, et al. Among authors: mourad aae. Biomed Pharmacother. 2023 Feb;158:114196. doi: 10.1016/j.biopha.2022.114196. Epub 2023 Jan 2. Biomed Pharmacother. 2023. PMID: 36916405 Free article.
29 results