Monaco G - Search Results

1

Profiling of the Bcl-2/Bcl-X(L)-binding sites on type 1 IP(3) receptor.

Monaco G, Beckers M, Ivanova H, Missiaen L, Parys JB, De Smedt H, Bultynck G. Monaco G, et al. Biochem Biophys Res Commun. 2012 Nov 9;428(1):31-5. doi: 10.1016/j.bbrc.2012.10.002. Epub 2012 Oct 8. Biochem Biophys Res Commun. 2012. PMID: 23058917

2

Selective regulation of IP3-receptor-mediated Ca2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl.

Monaco G, Decrock E, Akl H, Ponsaerts R, Vervliet T, Luyten T, De Maeyer M, Missiaen L, Distelhorst CW, De Smedt H, Parys JB, Leybaert L, Bultynck G. Monaco G, et al. Cell Death Differ. 2012 Feb;19(2):295-309. doi: 10.1038/cdd.2011.97. Epub 2011 Aug 5. Cell Death Differ. 2012. PMID: 21818117 Free PMC article.

3

IP3R2 levels dictate the apoptotic sensitivity of diffuse large B-cell lymphoma cells to an IP3R-derived peptide targeting the BH4 domain of Bcl-2.

Akl H, Monaco G, La Rovere R, Welkenhuyzen K, Kiviluoto S, Vervliet T, Molgó J, Distelhorst CW, Missiaen L, Mikoshiba K, Parys JB, De Smedt H, Bultynck G. Akl H, et al. Among authors: monaco g. Cell Death Dis. 2013 May 16;4(5):e632. doi: 10.1038/cddis.2013.140. Cell Death Dis. 2013. PMID: 23681227 Free PMC article.

4

The IP(3) receptor-mitochondria connection in apoptosis and autophagy.

Decuypere JP, Monaco G, Bultynck G, Missiaen L, De Smedt H, Parys JB. Decuypere JP, et al. Among authors: monaco g. Biochim Biophys Acta. 2011 May;1813(5):1003-13. doi: 10.1016/j.bbamcr.2010.11.023. Epub 2010 Dec 10. Biochim Biophys Acta. 2011. PMID: 21146562 Free article. Review.

5

IP(3) Receptors, Mitochondria, and Ca Signaling: Implications for Aging.

Decuypere JP, Monaco G, Missiaen L, De Smedt H, Parys JB, Bultynck G. Decuypere JP, et al. Among authors: monaco g. J Aging Res. 2011 Mar 8;2011:920178. doi: 10.4061/2011/920178. J Aging Res. 2011. PMID: 21423550 Free PMC article.

6

The selective BH4-domain biology of Bcl-2-family members: IP3Rs and beyond.

Monaco G, Vervliet T, Akl H, Bultynck G. Monaco G, et al. Cell Mol Life Sci. 2013 Apr;70(7):1171-83. doi: 10.1007/s00018-012-1118-y. Epub 2012 Sep 6. Cell Mol Life Sci. 2013. PMID: 22955373 Review.

7

Alpha-helical destabilization of the Bcl-2-BH4-domain peptide abolishes its ability to inhibit the IP3 receptor.

Monaco G, Decrock E, Nuyts K, Wagner LE 2nd, Luyten T, Strelkov SV, Missiaen L, De Borggraeve WM, Leybaert L, Yule DI, De Smedt H, Parys JB, Bultynck G. Monaco G, et al. PLoS One. 2013 Aug 30;8(8):e73386. doi: 10.1371/journal.pone.0073386. eCollection 2013. PLoS One. 2013. PMID: 24137498 Free PMC article.

8

The trans-membrane domain of Bcl-2α, but not its hydrophobic cleft, is a critical determinant for efficient IP3 receptor inhibition.

Ivanova H, Ritaine A, Wagner L, Luyten T, Shapovalov G, Welkenhuyzen K, Seitaj B, Monaco G, De Smedt H, Prevarskaya N, Yule DI, Parys JB, Bultynck G. Ivanova H, et al. Among authors: monaco g. Oncotarget. 2016 Aug 23;7(34):55704-55720. doi: 10.18632/oncotarget.11005. Oncotarget. 2016. PMID: 27494888 Free PMC article.

9

A double point mutation at residues Ile14 and Val15 of Bcl-2 uncovers a role for the BH4 domain in both protein stability and function.

Monaco G, La Rovere R, Karamanou S, Welkenhuyzen K, Ivanova H, Vandermarliere E, Di Martile M, Del Bufalo D, De Smedt H, Parys JB, Economou A, Bultynck G. Monaco G, et al. FEBS J. 2018 Jan;285(1):127-145. doi: 10.1111/febs.14324. Epub 2017 Dec 2. FEBS J. 2018. PMID: 29131545 Free article.

10

Pathophysiological consequences of isoform-specific IP₃ receptor mutations.

Kerkhofs M, Seitaj B, Ivanova H, Monaco G, Bultynck G, Parys JB. Kerkhofs M, et al. Among authors: monaco g. Biochim Biophys Acta Mol Cell Res. 2018 Nov;1865(11 Pt B):1707-1717. doi: 10.1016/j.bbamcr.2018.06.004. Epub 2018 Jun 12. Biochim Biophys Acta Mol Cell Res. 2018. PMID: 29906486 Free article. Review.

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