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mRNA aggregates harness danger response for potent cancer immunotherapy.
Mendez-Gomez HR, DeVries A, Castillo P, Stover BD, Qdaisat S, Von Roemeling C, Ogando-Rivas E, Weidert F, McGuiness J, Zhang D, Chung MC, Li D, Zhang C, Marconi C, Campaneria Y, Chardon-Robles J, Grippin A, Karachi A, Thomas N, Huang J, Milner R, Sahay B, Sawyer WG, Ligon JA, Silver N, Simon E, Cleaver B, Wynne K, Hodik M, Molinaro A, Guan J, Kellish P, Doty A, Lee JH, Carrera-Justiz S, Rahman M, Gatica S, Mueller S, Prados M, Ghiaseddin A, Mitchell DA, Sayour EJ. Mendez-Gomez HR, et al. Among authors: mitchell da. medRxiv [Preprint]. 2023 Mar 17:2023.03.12.23287108. doi: 10.1101/2023.03.12.23287108. medRxiv. 2023. PMID: 36993772 Free PMC article. Updated. Preprint.
Three-Dimensional Bioconjugated Liquid-Like Solid (LLS) Enhance Characterization of Solid Tumor - Chimeric Antigen Receptor T cell interactions.
Nguyen DT, Liu R, Ogando-Rivas E, Pepe A, Pedro D, Qdasait S, Nguyen NTY, Lavrador JM, Golde GR, Smolchek RA, Ligon J, Jin L, Tao H, Webber A, Phillpot S, Mitchell DA, Sayour EJ, Huang J, Castillo P, Sawyer WG. Nguyen DT, et al. Among authors: mitchell da. bioRxiv [Preprint]. 2023 Feb 21:2023.02.17.529033. doi: 10.1101/2023.02.17.529033. bioRxiv. 2023. PMID: 36865164 Free PMC article. Updated. Preprint.
mRNA challenge predicts brain cancer immunogenicity and response to checkpoint inhibitors.
Castillo P, Ogando-Rivas E, Geffrard H, Pepe A, Liu R, Nguyen DT, Pedro DI, Zhang D, DeVries A, Qdaisat S, Karachi A, Rahman M, Weidert F, Milner R, Huang J, Silver NL, Ligon J, Li D, Lee JH, Carrera-Justiz S, Mitchell DA, Mendez-Gomez H, Sawyer WG, Sayour EJ. Castillo P, et al. Among authors: mitchell da. bioRxiv [Preprint]. 2023 Mar 23:2023.03.18.532056. doi: 10.1101/2023.03.18.532056. bioRxiv. 2023. PMID: 36993158 Free PMC article. Preprint.
Expanded specific T cells to hypomutated regions of the SARS-CoV-2 using mRNA electroporated antigen-presenting cells.
Ogando-Rivas E, Castillo P, Yang C, Trivedi V, Zhang D, Pohl-Guimarães F, Liu R, Barpujari A, Candelario KM, Mendez-Gomez H, Sayour EJ, Mitchell DA. Ogando-Rivas E, et al. Among authors: mitchell da. Mol Ther Methods Clin Dev. 2024 Jan 22;32(1):101192. doi: 10.1016/j.omtm.2024.101192. eCollection 2024 Mar 14. Mol Ther Methods Clin Dev. 2024. PMID: 38327807 Free PMC article.
Evolution and Revolution of Imaging Technologies in Neurosurgery.
Ogando-Rivas E, Castillo P, Beltran JQ, Arellano R, Galvan-Remigio I, Soto-Ulloa V, Diaz-Peregrino R, Ochoa-Hernandez D, Reyes-González P, Sayour E, Mitchell D. Ogando-Rivas E, et al. Neurol Med Chir (Tokyo). 2022 Dec 15;62(12):542-551. doi: 10.2176/jns-nmc.2022-0116. Epub 2022 Oct 25. Neurol Med Chir (Tokyo). 2022. PMID: 36288973 Free PMC article.
KR158 spheres harboring slow-cycling cells recapitulate GBM features in an immunocompetent system.
Chakraborty A, Yang C, Kresak JL, Silver A, Feier D, Tian G, Andrews M, Sobanjo OO, Hodge ED, Engelbart MK, Huang J, Harrison JK, Sarkisian MR, Mitchell DA, Deleyrolle LP. Chakraborty A, et al. Among authors: mitchell da. bioRxiv [Preprint]. 2024 Jan 30:2024.01.26.577279. doi: 10.1101/2024.01.26.577279. bioRxiv. 2024. PMID: 38501121 Free PMC article. Preprint.
Cancer mRNA vaccines: clinical advances and future opportunities.
Sayour EJ, Boczkowski D, Mitchell DA, Nair SK. Sayour EJ, et al. Among authors: mitchell da. Nat Rev Clin Oncol. 2024 May 17. doi: 10.1038/s41571-024-00902-1. Online ahead of print. Nat Rev Clin Oncol. 2024. PMID: 38760500 Review.
RNA aggregates harness the danger response for potent cancer immunotherapy.
Mendez-Gomez HR, DeVries A, Castillo P, von Roemeling C, Qdaisat S, Stover BD, Xie C, Weidert F, Zhao C, Moor R, Liu R, Soni D, Ogando-Rivas E, Chardon-Robles J, McGuiness J, Zhang D, Chung MC, Marconi C, Michel S, Barpujari A, Jobin GW, Thomas N, Ma X, Campaneria Y, Grippin A, Karachi A, Li D, Sahay B, Elliott L, Foster TP, Coleman KE, Milner RJ, Sawyer WG, Ligon JA, Simon E, Cleaver B, Wynne K, Hodik M, Molinaro AM, Guan J, Kellish P, Doty A, Lee JH, Massini T, Kresak JL, Huang J, Hwang EI, Kline C, Carrera-Justiz S, Rahman M, Gatica S, Mueller S, Prados M, Ghiaseddin AP, Silver NL, Mitchell DA, Sayour EJ. Mendez-Gomez HR, et al. Among authors: mitchell da. Cell. 2024 May 9;187(10):2521-2535.e21. doi: 10.1016/j.cell.2024.04.003. Epub 2024 May 1. Cell. 2024. PMID: 38697107
587 results