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Novel HBsAg mutations correlate with hepatocellular carcinoma, hamper HBsAg secretion and promote cell proliferation in vitro.
Salpini R, Surdo M, Warner N, Cortese MF, Colledge D, Soppe S, Bellocchi MC, Armenia D, Carioti L, Continenza F, Di Carlo D, Saccomandi P, Mirabelli C, Pollicita M, Longo R, Romano S, Cappiello G, Spanò A, Trimoulet P, Fleury H, Vecchiet J, Iapadre N, Barlattani A, Bertoli A, Mari T, Pasquazzi C, Missale G, Sarrecchia C, Orecchini E, Michienzi A, Andreoni M, Francioso S, Angelico M, Verheyen J, Ceccherini-Silberstein F, Locarnini S, Perno CF, Svicher V. Salpini R, et al. Among authors: michienzi a. Oncotarget. 2017 Feb 28;8(9):15704-15715. doi: 10.18632/oncotarget.14944. Oncotarget. 2017. PMID: 28152517 Free PMC article.
The ADAR1 editing enzyme is encapsidated into HIV-1 virions.
Orecchini E, Federico M, Doria M, Arenaccio C, Giuliani E, Ciafrè SA, Michienzi A. Orecchini E, et al. Among authors: michienzi a. Virology. 2015 Nov;485:475-80. doi: 10.1016/j.virol.2015.07.027. Epub 2015 Sep 9. Virology. 2015. PMID: 26363218 Free article.
ADAR1 restricts LINE-1 retrotransposition.
Orecchini E, Doria M, Antonioni A, Galardi S, Ciafrè SA, Frassinelli L, Mancone C, Montaldo C, Tripodi M, Michienzi A. Orecchini E, et al. Among authors: michienzi a. Nucleic Acids Res. 2017 Jan 9;45(1):155-168. doi: 10.1093/nar/gkw834. Epub 2016 Sep 21. Nucleic Acids Res. 2017. PMID: 27658966 Free PMC article.
The RNA editing enzyme ADAR2 restricts L1 mobility.
Frassinelli L, Orecchini E, Al-Wardat S, Tripodi M, Mancone C, Doria M, Galardi S, Ciafrè SA, Michienzi A. Frassinelli L, et al. Among authors: michienzi a. RNA Biol. 2021 Oct 15;18(sup1):75-87. doi: 10.1080/15476286.2021.1940020. Epub 2021 Jul 5. RNA Biol. 2021. PMID: 34224323 Free PMC article.
Resetting cancer stem cell regulatory nodes upon MYC inhibition.
Galardi S, Savino M, Scagnoli F, Pellegatta S, Pisati F, Zambelli F, Illi B, Annibali D, Beji S, Orecchini E, Alberelli MA, Apicella C, Fontanella RA, Michienzi A, Finocchiaro G, Farace MG, Pavesi G, Ciafrè SA, Nasi S. Galardi S, et al. Among authors: michienzi a. EMBO Rep. 2016 Dec;17(12):1872-1889. doi: 10.15252/embr.201541489. Epub 2016 Nov 16. EMBO Rep. 2016. PMID: 27852622 Free PMC article.
The lncRNA H19 positively affects the tumorigenic properties of glioblastoma cells and contributes to NKD1 repression through the recruitment of EZH2 on its promoter.
Fazi B, Garbo S, Toschi N, Mangiola A, Lombari M, Sicari D, Battistelli C, Galardi S, Michienzi A, Trevisi G, Harari-Steinfeld R, Cicchini C, Ciafrè SA. Fazi B, et al. Among authors: michienzi a. Oncotarget. 2018 Feb 14;9(21):15512-15525. doi: 10.18632/oncotarget.24496. eCollection 2018 Mar 20. Oncotarget. 2018. PMID: 29643989 Free PMC article.
45 results