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Design, synthesis, and structure-activity relationship studies of a series of [4-(4-carboxamidobutyl)]-1-arylpiperazines: insights into structural features contributing to dopamine D3 versus D2 receptor subtype selectivity.
Ananthan S, Saini SK, Zhou G, Hobrath JV, Padmalayam I, Zhai L, Bostwick JR, Antonio T, Reith ME, McDowell S, Cho E, McAleer L, Taylor M, Luedtke RR. Ananthan S, et al. Among authors: mcaleer l. J Med Chem. 2014 Aug 28;57(16):7042-60. doi: 10.1021/jm500801r. Epub 2014 Aug 15. J Med Chem. 2014. PMID: 25126833 Free PMC article.
Weekend Ecstasy use disrupts memory in rats.
McAleer LM, Schallert T, Duvauchelle CL. McAleer LM, et al. Neurosci Lett. 2013 Aug 9;549:173-6. doi: 10.1016/j.neulet.2013.05.030. Epub 2013 May 22. Neurosci Lett. 2013. PMID: 23707649 Free PMC article.
Identification and hit-to-lead optimization of a novel class of CB1 antagonists.
Letourneau JJ, Jokiel P, Olson J, Riviello CM, Ho KK, McAleer L, Yang J, Swanson RN, Baker J, Cowley P, Edwards D, Ward N, Ohlmeyer MH, Webb ML. Letourneau JJ, et al. Among authors: mcaleer l. Bioorg Med Chem Lett. 2010 Sep 15;20(18):5449-53. doi: 10.1016/j.bmcl.2010.07.091. Epub 2010 Jul 25. Bioorg Med Chem Lett. 2010. PMID: 20719511