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Discovery of Selective Nanomolar Inhibitors for Insulin-Regulated Aminopeptidase Based on α-Hydroxy-β-amino Acid Derivatives of Bestatin.
Vourloumis D, Mavridis I, Athanasoulis A, Temponeras I, Koumantou D, Giastas P, Mpakali A, Magrioti V, Leib J, van Endert P, Stratikos E, Papakyriakou A. Vourloumis D, et al. Among authors: mavridis i. J Med Chem. 2022 Jul 28;65(14):10098-10117. doi: 10.1021/acs.jmedchem.2c00904. Epub 2022 Jul 14. J Med Chem. 2022. PMID: 35833347
Designed spiro-bicyclic analogues targeting the ribosomal decoding center.
Cottin T, Pyrkotis C, Stathakis CI, Mavridis I, Katsoulis IA, Anastasopoulou P, Kythreoti G, Zografos AL, Nahmias VR, Papakyriakou A, Vourloumis D. Cottin T, et al. Among authors: mavridis i. Chembiochem. 2011 Jan 3;12(1):71-87. doi: 10.1002/cbic.201000591. Chembiochem. 2011. PMID: 21154494
Synthesis of 5,6-spiroethers and evaluation of their affinities for the bacterial A site.
Katsoulis IA, Kythreoti G, Papakyriakou A, Koltsida K, Anastasopoulou P, Stathakis CI, Mavridis I, Cottin T, Saridakis E, Vourloumis D. Katsoulis IA, et al. Among authors: mavridis i. Chembiochem. 2011 May 16;12(8):1188-92. doi: 10.1002/cbic.201100076. Epub 2011 May 6. Chembiochem. 2011. PMID: 21557427 No abstract available.
Unnatural rigid scaffolds targeting the bacterial ribosome.
Katsoulis IA, Pyrkotis C, Papakyriakou A, Kythreoti G, Zografos AL, Mavridis I, Nahmias VR, Anastasopoulou P, Vourloumis D. Katsoulis IA, et al. Among authors: mavridis i. Chembiochem. 2009 Aug 17;10(12):1969-72. doi: 10.1002/cbic.200900268. Chembiochem. 2009. PMID: 19585638 No abstract available.
131 results