Synthesis of 5,6-spiroethers and evaluation of their affinities for the bacterial A site

Chembiochem. 2011 May 16;12(8):1188-92. doi: 10.1002/cbic.201100076. Epub 2011 May 6.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacteria / drug effects*
  • Binding Sites
  • Click Chemistry
  • Ethers, Cyclic / chemical synthesis*
  • Ethers, Cyclic / chemistry
  • Ethers, Cyclic / pharmacology*
  • Models, Molecular
  • Molecular Structure
  • Ribosomes / chemistry*
  • Ribosomes / metabolism
  • Spiro Compounds / chemical synthesis*
  • Spiro Compounds / chemistry
  • Spiro Compounds / pharmacology*

Substances

  • Ethers, Cyclic
  • Spiro Compounds
  • spiroether