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Ultra-high performance liquid chromatography tandem mass spectrometric method for the determination of tamoxifen, N-desmethyltamoxifen, 4-hydroxytamoxifen and endoxifen in dried blood spots--development, validation and clinical application during breast cancer adjuvant therapy.
Antunes MV, Raymundo S, de Oliveira V, Staudt DE, Gössling G, Peteffi GP, Biazús JV, Cavalheiro JA, Tre-Hardy M, Capron A, Haufroid V, Wallemacq P, Schwartsmann G, Linden R. Antunes MV, et al. Among authors: linden r. Talanta. 2015 Jan;132:775-84. doi: 10.1016/j.talanta.2014.10.040. Epub 2014 Oct 29. Talanta. 2015. PMID: 25476377 Free article.
CYP3A4*22 is related to increased plasma levels of 4-hydroxytamoxifen and partially compensates for reduced CYP2D6 activation of tamoxifen.
Antunes MV, de Oliveira V, Raymundo S, Staudt DE, Gössling G, Biazús JV, Cavalheiro JA, Rosa DD, Mathy G, Wallemacq P, Linden R, Schwartsmann G, Haufroid V. Antunes MV, et al. Among authors: linden r. Pharmacogenomics. 2015;16(6):601-17. doi: 10.2217/pgs.15.13. Epub 2015 Apr 20. Pharmacogenomics. 2015. PMID: 25893704
Improved determination of uracil and dihydrouracil in plasma after a loading oral dose of uracil using high-performance liquid chromatography with photodiode array detection and porous graphitic carbon stationary phase.
Hahn RZ, Galarza AF, Schneider A, Antunes MV, Schwartsmann G, Linden R. Hahn RZ, et al. Among authors: linden r. Clin Biochem. 2015 Sep;48(13-14):915-8. doi: 10.1016/j.clinbiochem.2015.04.019. Epub 2015 May 1. Clin Biochem. 2015. PMID: 25940841
765 results