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Virtual screening and biophysical studies lead to HSP90 inhibitors.
Huang R, Ayine-Tora DM, Muhammad Rosdi MN, Li Y, Reynisson J, Leung IKH. Huang R, et al. Among authors: leung ikh. Bioorg Med Chem Lett. 2017 Jan 15;27(2):277-281. doi: 10.1016/j.bmcl.2016.11.059. Epub 2016 Nov 23. Bioorg Med Chem Lett. 2017. PMID: 27913182
New Hydrazinothiazole Derivatives of Usnic Acid as Potent Tdp1 Inhibitors.
Filimonov AS, Chepanova AA, Luzina OA, Zakharenko AL, Zakharova OD, Ilina ES, Dyrkheeva NS, Kuprushkin MS, Kolotaev AV, Khachatryan DS, Patel J, Leung IKH, Chand R, Ayine-Tora DM, Reynisson J, Volcho KP, Salakhutdinov NF, Lavrik OI. Filimonov AS, et al. Among authors: leung ikh. Molecules. 2019 Oct 15;24(20):3711. doi: 10.3390/molecules24203711. Molecules. 2019. PMID: 31619021 Free PMC article.
Substrate specificity of polyphenol oxidase.
McLarin MA, Leung IKH. McLarin MA, et al. Among authors: leung ikh. Crit Rev Biochem Mol Biol. 2020 Jun;55(3):274-308. doi: 10.1080/10409238.2020.1768209. Epub 2020 May 22. Crit Rev Biochem Mol Biol. 2020. PMID: 32441137 Review.
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