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Page 1
Low glycaemic diets alter lipid metabolism to influence tumour growth.
Lien EC, Westermark AM, Zhang Y, Yuan C, Li Z, Lau AN, Sapp KM, Wolpin BM, Vander Heiden MG. Lien EC, et al. Among authors: lau an. Nature. 2021 Nov;599(7884):302-307. doi: 10.1038/s41586-021-04049-2. Epub 2021 Oct 20. Nature. 2021. PMID: 34671163 Free PMC article.
Altered exocrine function can drive adipose wasting in early pancreatic cancer.
Danai LV, Babic A, Rosenthal MH, Dennstedt EA, Muir A, Lien EC, Mayers JR, Tai K, Lau AN, Jones-Sali P, Prado CM, Petersen GM, Takahashi N, Sugimoto M, Yeh JJ, Lopez N, Bardeesy N, Fernandez-Del Castillo C, Liss AS, Koong AC, Bui J, Yuan C, Welch MW, Brais LK, Kulke MH, Dennis C, Clish CB, Wolpin BM, Vander Heiden MG. Danai LV, et al. Among authors: lau an. Nature. 2018 Jun;558(7711):600-604. doi: 10.1038/s41586-018-0235-7. Epub 2018 Jun 20. Nature. 2018. PMID: 29925948 Free PMC article.
Aspartate is an endogenous metabolic limitation for tumour growth.
Sullivan LB, Luengo A, Danai LV, Bush LN, Diehl FF, Hosios AM, Lau AN, Elmiligy S, Malstrom S, Lewis CA, Vander Heiden MG. Sullivan LB, et al. Among authors: lau an. Nat Cell Biol. 2018 Jul;20(7):782-788. doi: 10.1038/s41556-018-0125-0. Epub 2018 Jun 25. Nat Cell Biol. 2018. PMID: 29941931 Free PMC article.
Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma.
Lau AN, Li Z, Danai LV, Westermark AM, Darnell AM, Ferreira R, Gocheva V, Sivanand S, Lien EC, Sapp KM, Mayers JR, Biffi G, Chin CR, Davidson SM, Tuveson DA, Jacks T, Matheson NJ, Yilmaz O, Vander Heiden MG. Lau AN, et al. Elife. 2020 Jul 10;9:e56782. doi: 10.7554/eLife.56782. Elife. 2020. PMID: 32648540 Free PMC article.
Stopping the Clock with MYC.
Lau AN, Vander Heiden MG. Lau AN, et al. Mol Cell. 2015 Nov 19;60(4):511-3. doi: 10.1016/j.molcel.2015.11.008. Mol Cell. 2015. PMID: 26590710 Free article.
Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers.
Mayers JR, Torrence ME, Danai LV, Papagiannakopoulos T, Davidson SM, Bauer MR, Lau AN, Ji BW, Dixit PD, Hosios AM, Muir A, Chin CR, Freinkman E, Jacks T, Wolpin BM, Vitkup D, Vander Heiden MG. Mayers JR, et al. Among authors: lau an. Science. 2016 Sep 9;353(6304):1161-5. doi: 10.1126/science.aaf5171. Science. 2016. PMID: 27609895 Free PMC article.
Putting the K+ in K+aloric Restriction.
Lien EC, Lau AN, Vander Heiden MG. Lien EC, et al. Among authors: lau an. Immunity. 2019 May 21;50(5):1129-1131. doi: 10.1016/j.immuni.2019.04.016. Immunity. 2019. PMID: 31117009 Free article.
Increased PHGDH expression promotes aberrant melanin accumulation.
Mattaini KR, Sullivan MR, Lau AN, Fiske BP, Bronson RT, Vander Heiden MG. Mattaini KR, et al. Among authors: lau an. BMC Cancer. 2019 Jul 22;19(1):723. doi: 10.1186/s12885-019-5933-5. BMC Cancer. 2019. PMID: 31331318 Free PMC article.
Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance.
Dalin S, Sullivan MR, Lau AN, Grauman-Boss B, Mueller HS, Kreidl E, Fenoglio S, Luengo A, Lees JA, Vander Heiden MG, Lauffenburger DA, Hemann MT. Dalin S, et al. Among authors: lau an. Cancer Res. 2019 Nov 15;79(22):5723-5733. doi: 10.1158/0008-5472.CAN-19-0960. Epub 2019 Sep 4. Cancer Res. 2019. PMID: 31484670 Free PMC article.
50 results