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Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast-Driven Nutritional Support and Immunosuppression.
Francescone R, Barbosa Vendramini-Costa D, Franco-Barraza J, Wagner J, Muir A, Lau AN, Gabitova L, Pazina T, Gupta S, Luong T, Rollins D, Malik R, Thapa RJ, Restifo D, Zhou Y, Cai KQ, Hensley HH, Tan Y, Kruger WD, Devarajan K, Balachandran S, Klein-Szanto AJ, Wang H, El-Deiry WS, Vander Heiden MG, Peri S, Campbell KS, Astsaturov I, Cukierman E. Francescone R, et al. Among authors: lau an. Cancer Discov. 2021 Feb;11(2):446-479. doi: 10.1158/2159-8290.CD-20-0775. Epub 2020 Oct 30. Cancer Discov. 2021. PMID: 33127842 Free PMC article.
Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance.
Dalin S, Sullivan MR, Lau AN, Grauman-Boss B, Mueller HS, Kreidl E, Fenoglio S, Luengo A, Lees JA, Vander Heiden MG, Lauffenburger DA, Hemann MT. Dalin S, et al. Among authors: lau an. Cancer Res. 2019 Nov 15;79(22):5723-5733. doi: 10.1158/0008-5472.CAN-19-0960. Epub 2019 Sep 4. Cancer Res. 2019. PMID: 31484670 Free PMC article.
Putting the K+ in K+aloric Restriction.
Lien EC, Lau AN, Vander Heiden MG. Lien EC, et al. Among authors: lau an. Immunity. 2019 May 21;50(5):1129-1131. doi: 10.1016/j.immuni.2019.04.016. Immunity. 2019. PMID: 31117009 Free article.
Increased PHGDH expression promotes aberrant melanin accumulation.
Mattaini KR, Sullivan MR, Lau AN, Fiske BP, Bronson RT, Vander Heiden MG. Mattaini KR, et al. Among authors: lau an. BMC Cancer. 2019 Jul 22;19(1):723. doi: 10.1186/s12885-019-5933-5. BMC Cancer. 2019. PMID: 31331318 Free PMC article.
Stopping the Clock with MYC.
Lau AN, Vander Heiden MG. Lau AN, et al. Mol Cell. 2015 Nov 19;60(4):511-3. doi: 10.1016/j.molcel.2015.11.008. Mol Cell. 2015. PMID: 26590710 Free article.
PKM2 is not required for pancreatic ductal adenocarcinoma.
Hillis AL, Lau AN, Devoe CX, Dayton TL, Danai LV, Di Vizio D, Vander Heiden MG. Hillis AL, et al. Among authors: lau an. Cancer Metab. 2018 Oct 23;6:17. doi: 10.1186/s40170-018-0188-1. eCollection 2018. Cancer Metab. 2018. PMID: 30386596 Free PMC article.
Low glycaemic diets alter lipid metabolism to influence tumour growth.
Lien EC, Westermark AM, Zhang Y, Yuan C, Li Z, Lau AN, Sapp KM, Wolpin BM, Vander Heiden MG. Lien EC, et al. Among authors: lau an. Nature. 2021 Nov;599(7884):302-307. doi: 10.1038/s41586-021-04049-2. Epub 2021 Oct 20. Nature. 2021. PMID: 34671163 Free PMC article.
Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers.
Mayers JR, Torrence ME, Danai LV, Papagiannakopoulos T, Davidson SM, Bauer MR, Lau AN, Ji BW, Dixit PD, Hosios AM, Muir A, Chin CR, Freinkman E, Jacks T, Wolpin BM, Vitkup D, Vander Heiden MG. Mayers JR, et al. Among authors: lau an. Science. 2016 Sep 9;353(6304):1161-5. doi: 10.1126/science.aaf5171. Science. 2016. PMID: 27609895 Free PMC article.
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