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Oxidative damage to epigenetically methylated sites affects DNA stability, dynamics and enzymatic demethylation.
Gruber DR, Toner JJ, Miears HL, Shernyukov AV, Kiryutin AS, Lomzov AA, Endutkin AV, Grin IR, Petrova DV, Kupryushkin MS, Yurkovskaya AV, Johnson EC, Okon M, Bagryanskaya EG, Zharkov DO, Smirnov SL. Gruber DR, et al. Among authors: kupryushkin ms. Nucleic Acids Res. 2018 Nov 16;46(20):10827-10839. doi: 10.1093/nar/gky893. Nucleic Acids Res. 2018. PMID: 30289469 Free PMC article.
Antisense oligonucleotide gapmers containing phosphoryl guanidine groups reverse MDR1-mediated multiple drug resistance of tumor cells.
Kupryushkin MS, Filatov AV, Mironova NL, Patutina OA, Chernikov IV, Chernolovskaya EL, Zenkova MA, Pyshnyi DV, Stetsenko DA, Altman S, Vlassov VV. Kupryushkin MS, et al. Mol Ther Nucleic Acids. 2021 Nov 29;27:211-226. doi: 10.1016/j.omtn.2021.11.025. eCollection 2022 Mar 8. Mol Ther Nucleic Acids. 2021. PMID: 34976439 Free PMC article.
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