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Pathologic and molecular responses to neoadjuvant trastuzumab and/or lapatinib from a phase II randomized trial in HER2-positive breast cancer (TRIO-US B07).
Hurvitz SA, Caswell-Jin JL, McNamara KL, Zoeller JJ, Bean GR, Dichmann R, Perez A, Patel R, Zehngebot L, Allen H, Bosserman L, DiCarlo B, Kennedy A, Giuliano A, Calfa C, Molthrop D, Mani A, Chen HW, Dering J, Adams B, Kotler E, Press MF, Brugge JS, Curtis C, Slamon DJ. Hurvitz SA, et al. Among authors: kotler e. Nat Commun. 2020 Nov 17;11(1):5824. doi: 10.1038/s41467-020-19494-2. Nat Commun. 2020. PMID: 33203854 Free PMC article. Clinical Trial.
Deterministic evolution and stringent selection during preneoplasia.
Karlsson K, Przybilla MJ, Kotler E, Khan A, Xu H, Karagyozova K, Sockell A, Wong WH, Liu K, Mah A, Lo YH, Lu B, Houlahan KE, Ma Z, Suarez CJ, Barnes CP, Kuo CJ, Curtis C. Karlsson K, et al. Among authors: kotler e. Nature. 2023 Jun;618(7964):383-393. doi: 10.1038/s41586-023-06102-8. Epub 2023 May 31. Nature. 2023. PMID: 37258665 Free PMC article.
The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution.
Rozenblatt-Rosen O, Regev A, Oberdoerffer P, Nawy T, Hupalowska A, Rood JE, Ashenberg O, Cerami E, Coffey RJ, Demir E, Ding L, Esplin ED, Ford JM, Goecks J, Ghosh S, Gray JW, Guinney J, Hanlon SE, Hughes SK, Hwang ES, Iacobuzio-Donahue CA, Jané-Valbuena J, Johnson BE, Lau KS, Lively T, Mazzilli SA, Pe'er D, Santagata S, Shalek AK, Schapiro D, Snyder MP, Sorger PK, Spira AE, Srivastava S, Tan K, West RB, Williams EH; Human Tumor Atlas Network. Rozenblatt-Rosen O, et al. Cell. 2020 Apr 16;181(2):236-249. doi: 10.1016/j.cell.2020.03.053. Cell. 2020. PMID: 32302568 Free PMC article. Review.
p53 mutations promote proteasomal activity.
Oren M, Kotler E. Oren M, et al. Among authors: kotler e. Nat Cell Biol. 2016 Jul 27;18(8):833-5. doi: 10.1038/ncb3392. Nat Cell Biol. 2016. PMID: 27463250
RNF20 and USP44 regulate stem cell differentiation by modulating H2B monoubiquitylation.
Fuchs G, Shema E, Vesterman R, Kotler E, Wolchinsky Z, Wilder S, Golomb L, Pribluda A, Zhang F, Haj-Yahya M, Feldmesser E, Brik A, Yu X, Hanna J, Aberdam D, Domany E, Oren M. Fuchs G, et al. Among authors: kotler e. Mol Cell. 2012 Jun 8;46(5):662-73. doi: 10.1016/j.molcel.2012.05.023. Mol Cell. 2012. PMID: 22681888 Free PMC article.
N-methylation of isopeptide bond as a strategy to resist deubiquitinases.
Haj-Yahya M, Eltarteer N, Ohayon S, Shema E, Kotler E, Oren M, Brik A. Haj-Yahya M, et al. Among authors: kotler e. Angew Chem Int Ed Engl. 2012 Nov 12;51(46):11535-9. doi: 10.1002/anie.201205771. Epub 2012 Oct 12. Angew Chem Int Ed Engl. 2012. PMID: 23065695 No abstract available.
Regulatory module involving FGF13, miR-504, and p53 regulates ribosomal biogenesis and supports cancer cell survival.
Bublik DR, Bursać S, Sheffer M, Oršolić I, Shalit T, Tarcic O, Kotler E, Mouhadeb O, Hoffman Y, Fuchs G, Levin Y, Volarević S, Oren M. Bublik DR, et al. Among authors: kotler e. Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E496-E505. doi: 10.1073/pnas.1614876114. Epub 2016 Dec 19. Proc Natl Acad Sci U S A. 2017. PMID: 27994142 Free PMC article.
20 results