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Protein modification with ISG15 blocks coxsackievirus pathology by antiviral and metabolic reprogramming.
Kespohl M, Bredow C, Klingel K, Voß M, Paeschke A, Zickler M, Poller W, Kaya Z, Eckstein J, Fechner H, Spranger J, Fähling M, Wirth EK, Radoshevich L, Thery F, Impens F, Berndt N, Knobeloch KP, Beling A. Kespohl M, et al. Among authors: knobeloch kp. Sci Adv. 2020 Mar 11;6(11):eaay1109. doi: 10.1126/sciadv.aay1109. eCollection 2020 Mar. Sci Adv. 2020. PMID: 32195343 Free PMC article.
Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity.
Thery F, Martina L, Asselman C, Zhang Y, Vessely M, Repo H, Sedeyn K, Moschonas GD, Bredow C, Teo QW, Zhang J, Leandro K, Eggermont D, De Sutter D, Boucher K, Hochepied T, Festjens N, Callewaert N, Saelens X, Dermaut B, Knobeloch KP, Beling A, Sanyal S, Radoshevich L, Eyckerman S, Impens F. Thery F, et al. Among authors: knobeloch kp. Nat Commun. 2021 Oct 1;12(1):5772. doi: 10.1038/s41467-021-26061-w. Nat Commun. 2021. PMID: 34599178 Free PMC article.
ISG15 counteracts Listeria monocytogenes infection.
Radoshevich L, Impens F, Ribet D, Quereda JJ, Nam Tham T, Nahori MA, Bierne H, Dussurget O, Pizarro-Cerdá J, Knobeloch KP, Cossart P. Radoshevich L, et al. Among authors: knobeloch kp. Elife. 2015 Aug 11;4:e06848. doi: 10.7554/eLife.06848. Elife. 2015. PMID: 26259872 Free PMC article.
Strategies to Target ISG15 and USP18 Toward Therapeutic Applications.
Jiménez Fernández D, Hess S, Knobeloch KP. Jiménez Fernández D, et al. Among authors: knobeloch kp. Front Chem. 2020 Jan 21;7:923. doi: 10.3389/fchem.2019.00923. eCollection 2019. Front Chem. 2020. PMID: 32039148 Free PMC article. Review.
mHERC6 is the essential ISG15 E3 ligase in the murine system.
Ketscher L, Basters A, Prinz M, Knobeloch KP. Ketscher L, et al. Among authors: knobeloch kp. Biochem Biophys Res Commun. 2012 Jan 6;417(1):135-40. doi: 10.1016/j.bbrc.2011.11.071. Epub 2011 Nov 23. Biochem Biophys Res Commun. 2012. PMID: 22138649
Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity.
Shin D, Mukherjee R, Grewe D, Bojkova D, Baek K, Bhattacharya A, Schulz L, Widera M, Mehdipour AR, Tascher G, Geurink PP, Wilhelm A, van der Heden van Noort GJ, Ovaa H, Müller S, Knobeloch KP, Rajalingam K, Schulman BA, Cinatl J, Hummer G, Ciesek S, Dikic I. Shin D, et al. Among authors: knobeloch kp. Nature. 2020 Nov;587(7835):657-662. doi: 10.1038/s41586-020-2601-5. Epub 2020 Jul 29. Nature. 2020. PMID: 32726803 Free PMC article.
89 results