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Positive-strand RNA viruses-a Keystone Symposia report.
Cable J, Denison MR, Kielian M, Jackson WT, Bartenschlager R, Ahola T, Mukhopadhyay S, Fremont DH, Kuhn RJ, Shannon A, Frazier MN, Yuen KY, Coyne CB, Wolthers KC, Ming GL, Guenther CS, Moshiri J, Best SM, Schoggins JW, Jurado KA, Ebel GD, Schäfer A, Ng LFP, Kikkert M, Sette A, Harris E, Wing PAC, Eggenberger J, Krishnamurthy SR, Mah MG, Meganck RM, Chung D, Maurer-Stroh S, Andino R, Korber B, Perlman S, Shi PY, Bárcena M, Aicher SM, Vu MN, Kenney DJ, Lindenbach BD, Nishida Y, Rénia L, Williams EP. Cable J, et al. Among authors: kenney dj. Ann N Y Acad Sci. 2023 Mar;1521(1):46-66. doi: 10.1111/nyas.14957. Epub 2023 Jan 25. Ann N Y Acad Sci. 2023. PMID: 36697369 Free PMC article.
Cell culture systems for isolation of SARS-CoV-2 clinical isolates and generation of recombinant virus.
Chen DY, Turcinovic J, Feng S, Kenney DJ, Chin CV, Choudhary MC, Conway HL, Semaan M, Close BJ, Tavares AH, Seitz S, Khan N, Kapell S, Crossland NA, Li JZ, Douam F, Baker SC, Connor JH, Saeed M. Chen DY, et al. Among authors: kenney dj. iScience. 2023 May 19;26(5):106634. doi: 10.1016/j.isci.2023.106634. Epub 2023 Apr 10. iScience. 2023. PMID: 37095858 Free PMC article.
SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation.
Sanders DW, Jumper CC, Ackerman PJ, Bracha D, Donlic A, Kim H, Kenney D, Castello-Serrano I, Suzuki S, Tamura T, Tavares AH, Saeed M, Holehouse AS, Ploss A, Levental I, Douam F, Padera RF, Levy BD, Brangwynne CP. Sanders DW, et al. Elife. 2021 Apr 23;10:e65962. doi: 10.7554/eLife.65962. Elife. 2021. PMID: 33890572 Free PMC article.
SARS-CoV-2 Disrupts Proximal Elements in the JAK-STAT Pathway.
Chen DY, Khan N, Close BJ, Goel RK, Blum B, Tavares AH, Kenney D, Conway HL, Ewoldt JK, Chitalia VC, Crossland NA, Chen CS, Kotton DN, Baker SC, Fuchs SY, Connor JH, Douam F, Emili A, Saeed M. Chen DY, et al. J Virol. 2021 Sep 9;95(19):e0086221. doi: 10.1128/JVI.00862-21. Epub 2021 Sep 9. J Virol. 2021. PMID: 34260266 Free PMC article.
Evasion of NKG2D-mediated cytotoxic immunity by sarbecoviruses.
Hartmann JA, Cardoso MR, Talarico MCR, Kenney DJ, Leone MR, Reese DC, Turcinovic J, O'Connell AK, Gertje HP, Marino C, Ojeda PE, De Paula EV, Orsi FA, Velloso LA, Cafiero TR, Connor JH, Ploss A, Hoelzemer A, Carrington M, Barczak AK, Crossland NA, Douam F, Boucau J, Garcia-Beltran WF. Hartmann JA, et al. Among authors: kenney dj. Cell. 2024 Apr 11:S0092-8674(24)00317-9. doi: 10.1016/j.cell.2024.03.026. Online ahead of print. Cell. 2024. PMID: 38653235
Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression.
Carossino M, Kenney D, O'Connell AK, Montanaro P, Tseng AE, Gertje HP, Grosz KA, Ericsson M, Huber BR, Kurnick SA, Subramaniam S, Kirkland TA, Walker JR, Francis KP, Klose AD, Paragas N, Bosmann M, Saeed M, Balasuriya UBR, Douam F, Crossland NA. Carossino M, et al. Viruses. 2022 Mar 5;14(3):535. doi: 10.3390/v14030535. Viruses. 2022. PMID: 35336942 Free PMC article.
Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA.1 attenuation.
Chen DY, Chin CV, Kenney D, Tavares AH, Khan N, Conway HL, Liu G, Choudhary MC, Gertje HP, O'Connell AK, Adams S, Kotton DN, Herrmann A, Ensser A, Connor JH, Bosmann M, Li JZ, Gack MU, Baker SC, Kirchdoerfer RN, Kataria Y, Crossland NA, Douam F, Saeed M. Chen DY, et al. Nature. 2023 Mar;615(7950):143-150. doi: 10.1038/s41586-023-05697-2. Epub 2023 Jan 11. Nature. 2023. PMID: 36630998
12 results