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Integrated landscape of cardiac metabolism in end-stage human nonischemic dilated cardiomyopathy.
Flam E, Jang C, Murashige D, Yang Y, Morley MP, Jung S, Kantner DS, Pepper H, Bedi KC Jr, Brandimarto J, Prosser BL, Cappola T, Snyder NW, Rabinowitz JD, Margulies KB, Arany Z. Flam E, et al. Among authors: kantner ds. Nat Cardiovasc Res. 2022 Sep;1(9):817-829. doi: 10.1038/s44161-022-00117-6. Epub 2022 Aug 29. Nat Cardiovasc Res. 2022. PMID: 36776621 Free PMC article.
Acetylcarnitine shuttling links mitochondrial metabolism to histone acetylation and lipogenesis.
Izzo LT, Trefely S, Demetriadou C, Drummond JM, Mizukami T, Kuprasertkul N, Farria AT, Nguyen PTT, Murali N, Reich L, Kantner DS, Shaffer J, Affronti H, Carrer A, Andrews A, Capell BC, Snyder NW, Wellen KE. Izzo LT, et al. Among authors: kantner ds. Sci Adv. 2023 May 3;9(18):eadf0115. doi: 10.1126/sciadv.adf0115. Epub 2023 May 3. Sci Adv. 2023. PMID: 37134161 Free PMC article.
Chemoproteomics Yields a Selective Molecular Host for Acetyl-CoA.
Lieberman WK, Brown ZA, Kantner DS, Jing Y, Megill E, Evans ND, Crawford MC, Jhulki I, Grose C, Jones JE, Snyder NW, Meier JL. Lieberman WK, et al. Among authors: kantner ds. J Am Chem Soc. 2023 Aug 2;145(30):16899-16905. doi: 10.1021/jacs.3c05489. Epub 2023 Jul 24. J Am Chem Soc. 2023. PMID: 37486078
Lactoylglutathione promotes inflammatory signaling in macrophages through histone lactoylation.
Trujillo MN, Jennings EQ, Hoffman EA, Zhang H, Phoebe AM, Mastin GE, Kitamura N, Reisz JA, Megill E, Kantner D, Marcinkiewicz MM, Twardy SM, Lebario F, Chapman E, McCullough RL, D'Alessandro A, Snyder NW, Cusanovich DA, Galligan JJ. Trujillo MN, et al. Mol Metab. 2024 Mar;81:101888. doi: 10.1016/j.molmet.2024.101888. Epub 2024 Feb 1. Mol Metab. 2024. PMID: 38307385 Free PMC article.
Lactoylglutathione promotes inflammatory signaling in macrophages.
Trujillo MN, Jennings EQ, Hoffman EA, Zhang H, Phoebe AM, Mastin GE, Kitamura N, Reisz JA, Megill E, Kantner D, Marcinkiewicz MM, Twardy SM, Lebario F, Chapman E, McCullough RL, D'Alessandro A, Snyder NW, Cusanovich DA, Galligan JJ. Trujillo MN, et al. bioRxiv [Preprint]. 2023 Oct 10:2023.10.10.561739. doi: 10.1101/2023.10.10.561739. bioRxiv. 2023. PMID: 37873172 Free PMC article. Updated. Preprint.
αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation.
Uboveja A, Huang Z, Buj R, Amalric A, Wang H, Tangudu NK, Cole AR, Megill E, Kantner D, Chatoff A, Ahmad H, Marcinkiewicz MM, Disharoon JA, Graff S, Dahl ES, Hempel N, Stallaert W, Sidoli S, Bitler BG, Long DT, Snyder NW, Aird KM. Uboveja A, et al. bioRxiv [Preprint]. 2024 Feb 11:2024.02.06.578742. doi: 10.1101/2024.02.06.578742. bioRxiv. 2024. PMID: 38370789 Free PMC article. Preprint.
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