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Depletion of eukaryotic initiation factor 5B (eIF5B) reprograms the cellular transcriptome and leads to activation of endoplasmic reticulum (ER) stress and c-Jun N-terminal kinase (JNK).
Cell Stress Chaperones. 2021 Jan;26(1):253-264. doi: 10.1007/s12192-020-01174-1. Epub 2020 Oct 29.
Cell Stress Chaperones. 2021.
PMID: 33123915
Free PMC article.
Eukaryotic initiation factor 5B (eIF5B) regulates temozolomide-mediated apoptosis in brain tumour stem cells (BTSCs).
Ross JA, Ahn BY, King J, Bressler KR, Senger DL, Thakor N.
Ross JA, et al. Among authors: bressler kr.
Biochem Cell Biol. 2020 Dec;98(6):647-652. doi: 10.1139/bcb-2019-0329. Epub 2019 Oct 31.
Biochem Cell Biol. 2020.
PMID: 31671279
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Eukaryotic initiation factor 5B (eIF5B) provides a critical cell survival switch to glioblastoma cells via regulation of apoptosis.
Ross JA, Dungen KV, Bressler KR, Fredriksen M, Khandige Sharma D, Balasingam N, Thakor N.
Ross JA, et al. Among authors: bressler kr.
Cell Death Dis. 2019 Jan 22;10(2):57. doi: 10.1038/s41419-018-1283-5.
Cell Death Dis. 2019.
PMID: 30670698
Free PMC article.
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Eukaryotic Initiation Factor 5B (eIF5B) Cooperates with eIF1A and eIF5 to Facilitate uORF2-Mediated Repression of ATF4 Translation.
Ross JA, Bressler KR, Thakor N.
Ross JA, et al. Among authors: bressler kr.
Int J Mol Sci. 2018 Dec 13;19(12):4032. doi: 10.3390/ijms19124032.
Int J Mol Sci. 2018.
PMID: 30551605
Free PMC article.
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