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E-type prostanoid receptor 4 drives resolution of intestinal inflammation by blocking epithelial necroptosis.
Patankar JV, Müller TM, Kantham S, Acera MG, Mascia F, Scheibe K, Mahapatro M, Heichler C, Yu Y, Li W, Ruder B, Günther C, Leppkes M, Mathew MJ, Wirtz S, Neufert C, Kühl AA, Paquette J, Jacobson K, Atreya R, Zundler S, Neurath MF, Young RN, Becker C. Patankar JV, et al. Among authors: kuhl aa. Nat Cell Biol. 2021 Jul;23(7):796-807. doi: 10.1038/s41556-021-00708-8. Epub 2021 Jul 8. Nat Cell Biol. 2021. PMID: 34239062
Interleukin-7 links T lymphocyte and intestinal epithelial cell homeostasis.
Shalapour S, Deiser K, Kühl AA, Glauben R, Krug SM, Fischer A, Sercan O, Chappaz S, Bereswill S, Heimesaat MM, Loddenkemper C, Fromm M, Finke D, Hämmerling GJ, Arnold B, Siegmund B, Schüler T. Shalapour S, et al. Among authors: kuhl aa. PLoS One. 2012;7(2):e31939. doi: 10.1371/journal.pone.0031939. Epub 2012 Feb 27. PLoS One. 2012. PMID: 22384106 Free PMC article.
IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases.
Shen P, Roch T, Lampropoulou V, O'Connor RA, Stervbo U, Hilgenberg E, Ries S, Dang VD, Jaimes Y, Daridon C, Li R, Jouneau L, Boudinot P, Wilantri S, Sakwa I, Miyazaki Y, Leech MD, McPherson RC, Wirtz S, Neurath M, Hoehlig K, Meinl E, Grützkau A, Grün JR, Horn K, Kühl AA, Dörner T, Bar-Or A, Kaufmann SHE, Anderton SM, Fillatreau S. Shen P, et al. Among authors: kuhl aa. Nature. 2014 Mar 20;507(7492):366-370. doi: 10.1038/nature12979. Epub 2014 Feb 23. Nature. 2014. PMID: 24572363 Free PMC article.
c-FLIP is crucial for IL-7/IL-15-dependent NKp46+ ILC development and protection from intestinal inflammation in mice.
Bank U, Deiser K, Plaza-Sirvent C, Osbelt L, Witte A, Knop L, Labrenz R, Jänsch R, Richter F, Biswas A, Zenclussen AC, Vivier E, Romagnani C, Kühl AA, Dunay IR, Strowig T, Schmitz I, Schüler T. Bank U, et al. Among authors: kuhl aa. Nat Commun. 2020 Feb 26;11(1):1056. doi: 10.1038/s41467-020-14782-3. Nat Commun. 2020. PMID: 32103006 Free PMC article.
Severe Acute Respiratory Syndrome Coronavirus 2 Attachment Receptor Angiotensin-Converting Enzyme 2 Is Decreased in Crohn's Disease and Regulated By Microbial and Inflammatory Signaling.
Patankar JV, Chiriac MT, Lehmann M, Kühl AA, Atreya R, Becker C; Callaborators; Gonzalez-Acera M, Schmitt H, Gamez-Belmonte R, Mahapatro M, Diemand L, Hartmann L, Mascia F, Hracsko Z, Thonn V, Schödel L, Zielinska M, Yu Y, Erkert L, Li W, Zeitler M, Ruder B, Ganzleben I, Günther C, Voehringer D, Zundler S, Neurath MF, Siegmund B. Patankar JV, et al. Among authors: kuhl aa. Gastroenterology. 2021 Feb;160(3):925-928.e4. doi: 10.1053/j.gastro.2020.10.021. Epub 2020 Oct 17. Gastroenterology. 2021. PMID: 33075345 Free PMC article. No abstract available.
Maximizing the diagnostic information from biopsies in chronic inflammatory bowel diseases: recommendations from the Erlangen International Consensus Conference on Inflammatory Bowel Diseases and presentation of the IBD-DCA score as a proposal for a new index for histologic activity assessment in ulcerative colitis and Crohn's disease.
Lang-Schwarz C, Agaimy A, Atreya R, Becker C, Danese S, Fléjou JF, Gaßler N, Grabsch HI, Hartmann A, Kamarádová K, Kühl AA, Lauwers GY, Lugli A, Nagtegaal I, Neurath MF, Oberhuber G, Peyrin-Biroulet L, Rath T, Riddell R, Rubio CA, Sheahan K, Tilg H, Villanacci V, Westerhoff M, Vieth M. Lang-Schwarz C, et al. Among authors: kuhl aa. Virchows Arch. 2021 Mar;478(3):581-594. doi: 10.1007/s00428-020-02982-7. Epub 2020 Dec 29. Virchows Arch. 2021. PMID: 33373023 Free PMC article. No abstract available.
Validation of the 'Inflammatory Bowel Disease-Distribution, Chronicity, Activity [IBD-DCA] Score' for Ulcerative Colitis and Crohn´s Disease.
Lang-Schwarz C, Angeloni M, Agaimy A, Atreya R, Becker C, Dregelies T, Danese S, Fléjou JF, Gaßler N, Grabsch HI, Hartmann A, Kamarádová K, Kühl AA, Lauwers GY, Lugli A, Nagtegaal I, Neurath MF, Oberhuber G, Peyrin-Biroulet L, Rath T, Riddell R, Rubio CA, Sheahan K, Siegmund B, Tilg H, Villanacci V, Westerhoff M, Ferrazzi F, Vieth M. Lang-Schwarz C, et al. Among authors: kuhl aa. J Crohns Colitis. 2021 Oct 7;15(10):1621-1630. doi: 10.1093/ecco-jcc/jjab055. J Crohns Colitis. 2021. PMID: 33773497 Free PMC article.
Neutrophils prevent rectal bleeding in ulcerative colitis by peptidyl-arginine deiminase-4-dependent immunothrombosis.
Leppkes M, Lindemann A, Gößwein S, Paulus S, Roth D, Hartung A, Liebing E, Zundler S, Gonzalez-Acera M, Patankar JV, Mascia F, Scheibe K, Hoffmann M, Uderhardt S, Schauer C, Foersch S, Neufert C, Vieth M, Schett G, Atreya R, Kühl AA, Bleich A, Becker C, Herrmann M, Neurath MF. Leppkes M, et al. Among authors: kuhl aa. Gut. 2022 Dec;71(12):2414-2429. doi: 10.1136/gutjnl-2021-324725. Epub 2021 Dec 3. Gut. 2022. PMID: 34862250 Free PMC article.
224 results