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Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCL.
Eken JA, Koning MT, Kupcova K, Sepúlveda Yáñez JH, de Groen RAL, Quinten E, Janssen J, van Bergen CAM, Vermaat JSP, Cleven A, Navarrete MA, Ylstra B, de Jong D, Havranek O, Jumaa H, Veelken H. Eken JA, et al. Among authors: jumaa h. J Exp Med. 2024 May 6;221(5):e20230941. doi: 10.1084/jem.20230941. Epub 2024 Mar 21. J Exp Med. 2024. PMID: 38512136 Free PMC article.
Autonomous B-cell receptor signaling and genetic aberrations in chronic lymphocytic leukemia-phenotype monoclonal B lymphocytosis in siblings of patients with chronic lymphocytic leukemia.
Quinten E, Sepúlveda-Yáñez JH, Koning MT, Eken JA, Pfeifer D, Nteleah V, De Groen RAL, Saravia DA, Knijnenburg J, Stuivenberg-Bleijswijk HE, Pantic M, Agathangelidis A, Keppler-Hafkemeyer A, Van Bergen CAM, Uribe-Paredes R, Stamatopoulos K, Vermaat JSP, Zirlik K, Navarrete MA, Jumaa H, Veelken H. Quinten E, et al. Among authors: jumaa h. Haematologica. 2024 Mar 1;109(3):824-834. doi: 10.3324/haematol.2022.282542. Haematologica. 2024. PMID: 37439337 Free PMC article.
Targeted engagement of β-catenin-Ikaros complexes in refractory B-cell malignancies.
Cosgun KN, Jumaa H, Robinson ME, Kistner KM, Xu L, Xiao G, Chan LN, Lee J, Kume K, Leveille E, Fonseca-Arce D, Khanduja D, Ng HL, Feldhahn N, Song J, Chan WC, Chen J, Taketo MM, Kothari S, Davids MS, Schjerven H, Jellusova J, Müschen M. Cosgun KN, et al. Among authors: jumaa h. bioRxiv [Preprint]. 2023 Mar 15:2023.03.13.532152. doi: 10.1101/2023.03.13.532152. bioRxiv. 2023. PMID: 36993619 Free PMC article. Preprint.
Rheumatoid factor IgM autoantibodies control IgG homeostasis.
Nicolò A, Amendt T, El Ayoubi O, Young M, Finzel S, Senel M, Voll RE, Jumaa H. Nicolò A, et al. Among authors: jumaa h. Front Immunol. 2022 Oct 21;13:1016263. doi: 10.3389/fimmu.2022.1016263. eCollection 2022. Front Immunol. 2022. PMID: 36341420 Free PMC article.
Preclinical Evidence for the Efficacy of CD79b Immunotherapy in B-cell Precursor Acute Lymphoblastic Leukemia.
Lenk L, Winterberg D, Vogiatzi F, Laqua A, Spory L, Mayar A, Dietterle A, Münch G, Vokuhl C, Richter J, Polson AG, Schüler T, Kahlert UD, Peipp M, Valerius T, Schrappe M, Cario G, Jumaa H, Hobeika E, Brüggemann M, Alsadeq A, Schewe DM. Lenk L, et al. Among authors: jumaa h. Hemasphere. 2022 Jul 15;6(8):e754. doi: 10.1097/HS9.0000000000000754. eCollection 2022 Aug. Hemasphere. 2022. PMID: 35935606 Free PMC article. No abstract available.
The Small GTPase RHOA Links SLP65 Activation to PTEN Function in Pre B Cells and Is Essential for the Generation and Survival of Normal and Malignant B Cells.
Vadakumchery A, Faraidun H, Ayoubi OE, Outaleb I, Schmid V, Abdelrasoul H, Amendt T, Khadour A, Setz C, Göhring K, Lodd K, Hitzing C, Alkhatib A, Bilal M, Benckendorff J, Al Shugri AK, Brakebusch CH, Engels N, Datta M, Hobeika E, Alsadeq A, Jumaa H. Vadakumchery A, et al. Among authors: jumaa h. Front Immunol. 2022 Mar 15;13:842340. doi: 10.3389/fimmu.2022.842340. eCollection 2022. Front Immunol. 2022. PMID: 35371049 Free PMC article.
Autoreactive antibodies control blood glucose by regulating insulin homeostasis.
Amendt T, Allies G, Nicolò A, El Ayoubi O, Young M, Röszer T, Setz CS, Warnatz K, Jumaa H. Amendt T, et al. Among authors: jumaa h. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2115695119. doi: 10.1073/pnas.2115695119. Proc Natl Acad Sci U S A. 2022. PMID: 35131852 Free PMC article.
129 results