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An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity.
Borriello F, Poli V, Shrock E, Spreafico R, Liu X, Pishesha N, Carpenet C, Chou J, Di Gioia M, McGrath ME, Dillen CA, Barrett NA, Lacanfora L, Franco ME, Marongiu L, Iwakura Y, Pucci F, Kruppa MD, Ma Z, Lowman DW, Ensley HE, Nanishi E, Saito Y, O'Meara TR, Seo HS, Dhe-Paganon S, Dowling DJ, Frieman M, Elledge SJ, Levy O, Irvine DJ, Ploegh HL, Williams DL, Zanoni I. Borriello F, et al. Among authors: irvine dj. Cell. 2022 Feb 17;185(4):614-629.e21. doi: 10.1016/j.cell.2022.01.009. Epub 2022 Feb 10. Cell. 2022. PMID: 35148840 Free PMC article.
Synergistic innate and adaptive immune response to combination immunotherapy with anti-tumor antigen antibodies and extended serum half-life IL-2.
Zhu EF, Gai SA, Opel CF, Kwan BH, Surana R, Mihm MC, Kauke MJ, Moynihan KD, Angelini A, Williams RT, Stephan MT, Kim JS, Yaffe MB, Irvine DJ, Weiner LM, Dranoff G, Wittrup KD. Zhu EF, et al. Among authors: irvine dj. Cancer Cell. 2015 Apr 13;27(4):489-501. doi: 10.1016/j.ccell.2015.03.004. Cancer Cell. 2015. PMID: 25873172 Free PMC article.
An in vivo selection-derived d-peptide for engineering erythrocyte-binding antigens that promote immune tolerance.
Loftis AR, Zhang G, Backlund C, Quartararo AJ, Pishesha N, Hanna CC, Schissel CK, Garafola D, Loas A, Collier RJ, Ploegh H, Irvine DJ, Pentelute BL. Loftis AR, et al. Among authors: irvine dj. Proc Natl Acad Sci U S A. 2021 Aug 24;118(34):e2101596118. doi: 10.1073/pnas.2101596118. Proc Natl Acad Sci U S A. 2021. PMID: 34417313 Free PMC article.
Engineering New Approaches to Cancer Vaccines.
Mehta NK, Moynihan KD, Irvine DJ. Mehta NK, et al. Among authors: irvine dj. Cancer Immunol Res. 2015 Aug;3(8):836-43. doi: 10.1158/2326-6066.CIR-15-0112. Epub 2015 Jul 8. Cancer Immunol Res. 2015. PMID: 26156157 Free PMC article. Review.
A Receptor for All Occasions.
Irvine DJ. Irvine DJ. Cell. 2016 Feb 11;164(4):599-600. doi: 10.1016/j.cell.2016.01.030. Cell. 2016. PMID: 26871625 Free article.
306 results