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Sotigalimab and/or nivolumab with chemotherapy in first-line metastatic pancreatic cancer: clinical and immunologic analyses from the randomized phase 2 PRINCE trial.
Padrón LJ, Maurer DM, O'Hara MH, O'Reilly EM, Wolff RA, Wainberg ZA, Ko AH, Fisher G, Rahma O, Lyman JP, Cabanski CR, Yu JX, Pfeiffer SM, Spasic M, Xu J, Gherardini PF, Karakunnel J, Mick R, Alanio C, Byrne KT, Hollmann TJ, Moore JS, Jones DD, Tognetti M, Chen RO, Yang X, Salvador L, Wherry EJ, Dugan U, O'Donnell-Tormey J, Butterfield LH, Hubbard-Lucey VM, Ibrahim R, Fairchild J, Bucktrout S, LaVallee TM, Vonderheide RH. Padrón LJ, et al. Among authors: hubbard lucey vm. Nat Med. 2022 Jun;28(6):1167-1177. doi: 10.1038/s41591-022-01829-9. Epub 2022 Jun 3. Nat Med. 2022. PMID: 35662283 Free PMC article. Clinical Trial.
CD40 agonistic monoclonal antibody APX005M (sotigalimab) and chemotherapy, with or without nivolumab, for the treatment of metastatic pancreatic adenocarcinoma: an open-label, multicentre, phase 1b study.
O'Hara MH, O'Reilly EM, Varadhachary G, Wolff RA, Wainberg ZA, Ko AH, Fisher G, Rahma O, Lyman JP, Cabanski CR, Mick R, Gherardini PF, Kitch LJ, Xu J, Samuel T, Karakunnel J, Fairchild J, Bucktrout S, LaVallee TM, Selinsky C, Till JE, Carpenter EL, Alanio C, Byrne KT, Chen RO, Trifan OC, Dugan U, Horak C, Hubbard-Lucey VM, Wherry EJ, Ibrahim R, Vonderheide RH. O'Hara MH, et al. Among authors: hubbard lucey vm. Lancet Oncol. 2021 Jan;22(1):118-131. doi: 10.1016/S1470-2045(20)30532-5. Lancet Oncol. 2021. PMID: 33387490 Clinical Trial.
The global landscape of cancer cell therapy.
Tang J, Hubbard-Lucey VM, Pearce L, O'Donnell-Tormey J, Shalabi A. Tang J, et al. Nat Rev Drug Discov. 2018 Jul;17(7):465-466. doi: 10.1038/nrd.2018.74. Epub 2018 May 25. Nat Rev Drug Discov. 2018. PMID: 29795477 No abstract available.
Trends in the global immuno-oncology landscape.
Tang J, Pearce L, O'Donnell-Tormey J, Hubbard-Lucey VM. Tang J, et al. Nat Rev Drug Discov. 2018 Nov;17(11):783-784. doi: 10.1038/nrd.2018.167. Epub 2018 Oct 19. Nat Rev Drug Discov. 2018. PMID: 30337722 No abstract available.
Immuno-oncology drug development forges on despite COVID-19.
Upadhaya S, Hubbard-Lucey VM, Yu JX. Upadhaya S, et al. Among authors: hubbard lucey vm. Nat Rev Drug Discov. 2020 Nov;19(11):751-752. doi: 10.1038/d41573-020-00166-1. Nat Rev Drug Discov. 2020. PMID: 32948858 No abstract available.
Defining tumor resistance to PD-1 pathway blockade: recommendations from the first meeting of the SITC Immunotherapy Resistance Taskforce.
Kluger HM, Tawbi HA, Ascierto ML, Bowden M, Callahan MK, Cha E, Chen HX, Drake CG, Feltquate DM, Ferris RL, Gulley JL, Gupta S, Humphrey RW, LaVallee TM, Le DT, Hubbard-Lucey VM, Papadimitrakopoulou VA, Postow MA, Rubin EH, Sharon E, Taube JM, Topalian SL, Zappasodi R, Sznol M, Sullivan RJ. Kluger HM, et al. Among authors: hubbard lucey vm. J Immunother Cancer. 2020 Mar;8(1):e000398. doi: 10.1136/jitc-2019-000398. J Immunother Cancer. 2020. PMID: 32238470 Free PMC article.
Cancer cell therapies: the clinical trial landscape.
Yu JX, Upadhaya S, Tatake R, Barkalow F, Hubbard-Lucey VM. Yu JX, et al. Among authors: hubbard lucey vm. Nat Rev Drug Discov. 2020 Sep;19(9):583-584. doi: 10.1038/d41573-020-00099-9. Nat Rev Drug Discov. 2020. PMID: 32457476 No abstract available.
Trends in the global immuno-oncology landscape.
Tang J, Pearce L, O'Donnell-Tormey J, Hubbard-Lucey VM. Tang J, et al. Nat Rev Drug Discov. 2018 Dec;17(12):922. doi: 10.1038/nrd.2018.202. Epub 2018 Oct 26. Nat Rev Drug Discov. 2018. PMID: 30361553
24 results