Hu J - Search Results

1

Engineering of efficiency-enhanced Cas9 and base editors with improved gene therapy efficacies.

Yin S, Zhang M, Liu Y, Sun X, Guan Y, Chen X, Yang L, Huo Y, Yang J, Zhang X, Han H, Zhang J, Xiao MM, Liu M, Hu J, Wang L, Li D. Yin S, et al. Among authors: hu j. Mol Ther. 2023 Mar 1;31(3):744-759. doi: 10.1016/j.ymthe.2022.11.014. Epub 2022 Nov 30. Mol Ther. 2023. PMID: 36457249 Free PMC article.

2

Optimizing genome editing strategy by primer-extension-mediated sequencing.

Yin J, Liu M, Liu Y, Wu J, Gan T, Zhang W, Li Y, Zhou Y, Hu J. Yin J, et al. Among authors: hu j. Cell Discov. 2019 Mar 26;5:18. doi: 10.1038/s41421-019-0088-8. eCollection 2019. Cell Discov. 2019. PMID: 30937179 Free PMC article.

3

Improved HTGTS for CRISPR/Cas9 off-target detection.

Yin J, Liu M, Liu Y, Hu J. Yin J, et al. Among authors: hu j. Bio Protoc. 2019 May 5;9(9):e3229. doi: 10.21769/BioProtoc.3229. eCollection 2019 May 5. Bio Protoc. 2019. PMID: 33655015 Free PMC article.

4

Transcription shapes DNA replication initiation to preserve genome integrity.

Liu Y, Ai C, Gan T, Wu J, Jiang Y, Liu X, Lu R, Gao N, Li Q, Ji X, Hu J. Liu Y, et al. Among authors: hu j. Genome Biol. 2021 Jun 9;22(1):176. doi: 10.1186/s13059-021-02390-3. Genome Biol. 2021. PMID: 34108027 Free PMC article.

5

RAG2 abolishes RAG1 aggregation to facilitate V(D)J recombination.

Gan T, Wang Y, Liu Y, Schatz DG, Hu J. Gan T, et al. Among authors: hu j. Cell Rep. 2021 Oct 12;37(2):109824. doi: 10.1016/j.celrep.2021.109824. Cell Rep. 2021. PMID: 34644584 Free PMC article.

6

PEM-seq comprehensively quantifies DNA repair outcomes during gene-editing and DSB repair.

Liu Y, Yin J, Gan T, Liu M, Xin C, Zhang W, Hu J. Liu Y, et al. Among authors: hu j. STAR Protoc. 2022 Jan 17;3(1):101088. doi: 10.1016/j.xpro.2021.101088. eCollection 2022 Mar 18. STAR Protoc. 2022. PMID: 35462794 Free PMC article.

7

Long-term correction of hemophilia B through CRISPR/Cas9 induced homology-independent targeted integration.

Chen X, Niu X, Liu Y, Zheng R, Yang L, Lu J, Yin S, Wei Y, Pan J, Sayed A, Ma X, Liu M, Jing F, Liu M, Hu J, Wang L, Li D. Chen X, et al. Among authors: hu j. J Genet Genomics. 2022 Dec;49(12):1114-1126. doi: 10.1016/j.jgg.2022.06.001. Epub 2022 Jun 9. J Genet Genomics. 2022. PMID: 35691554

8

CRISPR/Cas9-induced structural variations expand in T lymphocytes in vivo.

Wu J, Zou Z, Liu Y, Liu X, Zhangding Z, Xu M, Hu J. Wu J, et al. Among authors: hu j. Nucleic Acids Res. 2022 Oct 28;50(19):11128-11137. doi: 10.1093/nar/gkac887. Nucleic Acids Res. 2022. PMID: 36243978 Free PMC article.

9

Erratum: Correction Notice: Improved HTGTS for CRISPR/Cas9 Off-target Detection.

Yin J, Liu M, Liu Y, Hu J. Yin J, et al. Among authors: hu j. Bio Protoc. 2019 Dec 5;9(23):e3462. doi: 10.21769/BioProtoc.3462. eCollection 2019 Dec 5. Bio Protoc. 2019. PMID: 38155635 Free PMC article.

10

Fork coupling directs DNA replication elongation and termination.

Liu Y, Zhangding Z, Liu X, Gan T, Ai C, Wu J, Liang H, Chen M, Guo Y, Lu R, Jiang Y, Ji X, Gao N, Kong D, Li Q, Hu J. Liu Y, et al. Among authors: hu j. Science. 2024 Mar 15;383(6688):1215-1222. doi: 10.1126/science.adj7606. Epub 2024 Mar 14. Science. 2024. PMID: 38484065

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