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A prospective compound screening contest identified broader inhibitors for Sirtuin 1.
Chiba S, Ohue M, Gryniukova A, Borysko P, Zozulya S, Yasuo N, Yoshino R, Ikeda K, Shin WH, Kihara D, Iwadate M, Umeyama H, Ichikawa T, Teramoto R, Hsin KY, Gupta V, Kitano H, Sakamoto M, Higuchi A, Miura N, Yura K, Mochizuki M, Ramakrishnan C, Thangakani AM, Velmurugan D, Gromiha MM, Nakane I, Uchida N, Hakariya H, Tan M, Nakamura HK, Suzuki SD, Ito T, Kawatani M, Kudoh K, Takashina S, Yamamoto KZ, Moriwaki Y, Oda K, Kobayashi D, Okuno T, Minami S, Chikenji G, Prathipati P, Nagao C, Mohsen A, Ito M, Mizuguchi K, Honma T, Ishida T, Hirokawa T, Akiyama Y, Sekijima M. Chiba S, et al. Among authors: hsin ky. Sci Rep. 2019 Dec 20;9(1):19585. doi: 10.1038/s41598-019-55069-y. Sci Rep. 2019. PMID: 31863054 Free PMC article.
Identification of potential inhibitors based on compound proposal contest: Tyrosine-protein kinase Yes as a target.
Chiba S, Ikeda K, Ishida T, Gromiha MM, Taguchi YH, Iwadate M, Umeyama H, Hsin KY, Kitano H, Yamamoto K, Sugaya N, Kato K, Okuno T, Chikenji G, Mochizuki M, Yasuo N, Yoshino R, Yanagisawa K, Ban T, Teramoto R, Ramakrishnan C, Thangakani AM, Velmurugan D, Prathipati P, Ito J, Tsuchiya Y, Mizuguchi K, Honma T, Hirokawa T, Akiyama Y, Sekijima M. Chiba S, et al. Among authors: hsin ky. Sci Rep. 2015 Nov 26;5:17209. doi: 10.1038/srep17209. Sci Rep. 2015. PMID: 26607293 Free PMC article.
Toward an integrated software platform for systems pharmacology.
Ghosh S, Matsuoka Y, Asai Y, Hsin KY, Kitano H. Ghosh S, et al. Among authors: hsin ky. Biopharm Drug Dispos. 2013 Dec;34(9):508-26. doi: 10.1002/bdd.1875. Biopharm Drug Dispos. 2013. PMID: 24150748 Free PMC article. Review.
An improved strategy for the crystallization of Leishmania mexicana pyruvate kinase.
Morgan HP, McNae IW, Hsin KY, Michels PA, Fothergill-Gilmore LA, Walkinshaw MD. Morgan HP, et al. Among authors: hsin ky. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Mar 1;66(Pt 3):215-8. doi: 10.1107/S1744309109053494. Epub 2010 Feb 23. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 20208146 Free PMC article.
16 results