Hixon M - Search Results

1

Risk of rapid evolutionary escape from biomedical interventions targeting SARS-CoV-2 spike protein.

Van Egeren D, Novokhodko A, Stoddard M, Tran U, Zetter B, Rogers M, Pentelute BL, Carlson JM, Hixon M, Joseph-McCarthy D, Chakravarty A. Van Egeren D, et al. Among authors: hixon m. PLoS One. 2021 Apr 28;16(4):e0250780. doi: 10.1371/journal.pone.0250780. eCollection 2021. PLoS One. 2021. PMID: 33909660 Free PMC article.

2

Quo vadis photorespiration: a tale of two aldolases.

Hixon M, Sinerius G, Schneider A, Walter C, Fessner WD, Schloss JV. Hixon M, et al. FEBS Lett. 1996 Sep 2;392(3):281-4. doi: 10.1016/0014-5793(96)00830-7. FEBS Lett. 1996. PMID: 8774862 Free article.

3

Beta-alanine transaminase activity in black and suppressor of black mutations of Drosophila melanogaster.

Weber JP, Bolin RJ, Hixon MS, Sherald AF. Weber JP, et al. Among authors: hixon ms. Biochim Biophys Acta. 1992 Jan 23;1115(3):181-6. doi: 10.1016/0304-4165(92)90051-u. Biochim Biophys Acta. 1992. PMID: 1739732

4

A fragment-based approach to identifying S-adenosyl-l-methionine -competitive inhibitors of catechol O-methyl transferase (COMT).

Lanier M, Ambrus G, Cole DC, Davenport R, Ellery J, Fosbeary R, Jennings AJ, Kadotani A, Kamada Y, Kamran R, Matsumoto S, Mizukami A, Okubo S, Okada K, Saikatendu K, Walsh L, Wu H, Hixon MS. Lanier M, et al. Among authors: hixon ms. J Med Chem. 2014 Jun 26;57(12):5459-63. doi: 10.1021/jm500475k. Epub 2014 Jun 4. J Med Chem. 2014. PMID: 24847974

5

Biochemical characterization of a novel type-II VEGFR2 kinase inhibitor: comparison of binding to non-phosphorylated and phosphorylated VEGFR2.

Iwata H, Imamura S, Hori A, Hixon MS, Kimura H, Miki H. Iwata H, et al. Bioorg Med Chem. 2011 Sep 15;19(18):5342-51. doi: 10.1016/j.bmc.2011.08.002. Epub 2011 Aug 6. Bioorg Med Chem. 2011. PMID: 21885287

6

Discovery of novel benzo[b][1,4]oxazin-3(4H)-ones as poly(ADP-ribose)polymerase inhibitors.

Gangloff AR, Brown J, de Jong R, Dougan DR, Grimshaw CE, Hixon M, Jennings A, Kamran R, Kiryanov A, O'Connell S, Taylor E, Vu P. Gangloff AR, et al. Among authors: hixon m. Bioorg Med Chem Lett. 2013 Aug 15;23(16):4501-5. doi: 10.1016/j.bmcl.2013.06.055. Epub 2013 Jun 24. Bioorg Med Chem Lett. 2013. PMID: 23850199

7

A Back-to-Front Fragment-Based Drug Design Search Strategy Targeting the DFG-Out Pocket of Protein Tyrosine Kinases.

Iwata H, Oki H, Okada K, Takagi T, Tawada M, Miyazaki Y, Imamura S, Hori A, Lawson JD, Hixon MS, Kimura H, Miki H. Iwata H, et al. Among authors: hixon ms. ACS Med Chem Lett. 2012 Feb 28;3(4):342-6. doi: 10.1021/ml3000403. eCollection 2012 Apr 12. ACS Med Chem Lett. 2012. PMID: 24900475 Free PMC article.

8

Benzoquinones as inhibitors of botulinum neurotoxin serotype A.

Bremer PT, Hixon MS, Janda KD. Bremer PT, et al. Bioorg Med Chem. 2014 Aug 1;22(15):3971-81. doi: 10.1016/j.bmc.2014.06.004. Epub 2014 Jun 16. Bioorg Med Chem. 2014. PMID: 24984937 Free PMC article.

9

A simple and widely applicable hit validation strategy for protein-protein interaction inhibitors based on a quantitative ligand displacement assay.

Sameshima T, Miyahisa I, Homma M, Aikawa K, Hixon MS, Matsui J. Sameshima T, et al. Among authors: hixon ms. Bioorg Med Chem Lett. 2014 Dec 15;24(24):5836-5839. doi: 10.1016/j.bmcl.2014.09.073. Epub 2014 Oct 2. Bioorg Med Chem Lett. 2014. PMID: 25452002

10

Fragment-based drug discovery of potent and selective MKK3/6 inhibitors.

Adams M, Kobayashi T, Lawson JD, Saitoh M, Shimokawa K, Bigi SV, Hixon MS, Smith CR, Tatamiya T, Goto M, Russo J, Grimshaw CE, Swann S. Adams M, et al. Among authors: hixon ms. Bioorg Med Chem Lett. 2016 Feb 1;26(3):1086-1089. doi: 10.1016/j.bmcl.2015.11.054. Epub 2015 Nov 17. Bioorg Med Chem Lett. 2016. PMID: 26704264

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