Beta-alanine transaminase activity in black and suppressor of black mutations of Drosophila melanogaster

J P Weber; R J Bolin; M S Hixon; A F Sherald

doi:10.1016/0304-4165(92)90051-u

Beta-alanine transaminase activity in black and suppressor of black mutations of Drosophila melanogaster

Biochim Biophys Acta. 1992 Jan 23;1115(3):181-6. doi: 10.1016/0304-4165(92)90051-u.

Authors

J P Weber¹, R J Bolin, M S Hixon, A F Sherald

Affiliation

¹ Department of Chemistry, George Mason University, Fairfax, VA 22030.

PMID: 1739732
DOI: 10.1016/0304-4165(92)90051-u

Abstract

An assay for beta-alanine transaminase activity in extracts of Drosophila melanogaster has been developed. By use of this assay, the levels of beta-alanine transaminase activity in several strains of flies has been examined as a function of developmental age. The black mutation shows elevated levels of activity compared to wild type, while suppressor of black strains show decreased levels compared to wild type.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

4-Aminobutyrate Transaminase / metabolism*
Animals
Drosophila melanogaster / enzymology
Drosophila melanogaster / genetics*
Drosophila melanogaster / growth & development
Glutamate Dehydrogenase / metabolism
Kinetics
Pigmentation / genetics*
beta-Alanine / metabolism

Substances

beta-Alanine
Glutamate Dehydrogenase
4-Aminobutyrate Transaminase