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Inhibition of Mitochondrial Dynamics Preferentially Targets Pancreatic Cancer Cells with Enhanced Tumorigenic and Invasive Potential.
Courtois S, de Luxán-Delgado B, Penin-Peyta L, Royo-García A, Parejo-Alonso B, Jagust P, Alcalá S, Rubiolo JA, Sánchez L, Sainz B Jr, Heeschen C, Sancho P. Courtois S, et al. Among authors: heeschen c. Cancers (Basel). 2021 Feb 9;13(4):698. doi: 10.3390/cancers13040698. Cancers (Basel). 2021. PMID: 33572276 Free PMC article.
Nodal/Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy.
Lonardo E, Hermann PC, Mueller MT, Huber S, Balic A, Miranda-Lorenzo I, Zagorac S, Alcala S, Rodriguez-Arabaolaza I, Ramirez JC, Torres-Ruíz R, Garcia E, Hidalgo M, Cebrián DÁ, Heuchel R, Löhr M, Berger F, Bartenstein P, Aicher A, Heeschen C. Lonardo E, et al. Among authors: heeschen c. Cell Stem Cell. 2011 Nov 4;9(5):433-46. doi: 10.1016/j.stem.2011.10.001. Cell Stem Cell. 2011. PMID: 22056140 Free article.
Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.
Hermann PC, Sancho P, Cañamero M, Martinelli P, Madriles F, Michl P, Gress T, de Pascual R, Gandia L, Guerra C, Barbacid M, Wagner M, Vieira CR, Aicher A, Real FX, Sainz B Jr, Heeschen C. Hermann PC, et al. Among authors: heeschen c. Gastroenterology. 2014 Nov;147(5):1119-33.e4. doi: 10.1053/j.gastro.2014.08.002. Epub 2014 Aug 12. Gastroenterology. 2014. PMID: 25127677
Intracellular autofluorescence: a biomarker for epithelial cancer stem cells.
Miranda-Lorenzo I, Dorado J, Lonardo E, Alcala S, Serrano AG, Clausell-Tormos J, Cioffi M, Megias D, Zagorac S, Balic A, Hidalgo M, Erkan M, Kleeff J, Scarpa A, Sainz B Jr, Heeschen C. Miranda-Lorenzo I, et al. Among authors: heeschen c. Nat Methods. 2014 Nov;11(11):1161-9. doi: 10.1038/nmeth.3112. Epub 2014 Sep 28. Nat Methods. 2014. PMID: 25262208
153 results