Hao-Shen H - Search Results

1

JAK2-V617F and interferon-α induce megakaryocyte-biased stem cells characterized by decreased long-term functionality.

Rao TN, Hansen N, Stetka J, Luque Paz D, Kalmer M, Hilfiker J, Endele M, Ahmed N, Kubovcakova L, Rybarikova M, Hao-Shen H, Geier F, Beisel C, Dirnhofer S, Schroeder T, Brümmendorf TH, Wolf D, Koschmieder S, Skoda RC. Rao TN, et al. Among authors: hao shen h. Blood. 2021 Apr 22;137(16):2139-2151. doi: 10.1182/blood.2020005563. Blood. 2021. PMID: 33667305 Free PMC article.

2

Pf4-Cre transgenic mice allow the generation of lineage-restricted gene knockouts for studying megakaryocyte and platelet function in vivo.

Tiedt R, Schomber T, Hao-Shen H, Skoda RC. Tiedt R, et al. Blood. 2007 Feb 15;109(4):1503-6. doi: 10.1182/blood-2006-04-020362. Epub 2006 Oct 10. Blood. 2007. PMID: 17032923 Free article.

3

Normal erythropoiesis but severe polyposis and bleeding anemia in Smad4-deficient mice.

Pan D, Schomber T, Kalberer CP, Terracciano LM, Hafen K, Krenger W, Hao-Shen H, Deng C, Skoda RC. Pan D, et al. Blood. 2007 Oct 15;110(8):3049-55. doi: 10.1182/blood-2007-02-074393. Epub 2007 Jul 16. Blood. 2007. PMID: 17638848 Free article.

4

Ratio of mutant JAK2-V617F to wild-type Jak2 determines the MPD phenotypes in transgenic mice.

Tiedt R, Hao-Shen H, Sobas MA, Looser R, Dirnhofer S, Schwaller J, Skoda RC. Tiedt R, et al. Blood. 2008 Apr 15;111(8):3931-40. doi: 10.1182/blood-2007-08-107748. Epub 2007 Dec 26. Blood. 2008. PMID: 18160670 Free article.

5

The allele burden of JAK2 mutations remains stable over several years in patients with myeloproliferative disorders.

Theocharides A, Passweg JR, Medinger M, Looser R, Li S, Hao-Shen H, Buser AS, Gratwohl A, Tichelli A, Skoda RC. Theocharides A, et al. Haematologica. 2008 Dec;93(12):1890-3. doi: 10.3324/haematol.13074. Epub 2008 Sep 11. Haematologica. 2008. PMID: 18790796 Free article.

6

Pronounced thrombocytosis in transgenic mice expressing reduced levels of Mpl in platelets and terminally differentiated megakaryocytes.

Tiedt R, Coers J, Ziegler S, Wiestner A, Hao-Shen H, Bornmann C, Schenkel J, Karakhanova S, de Sauvage FJ, Jackson CW, Skoda RC. Tiedt R, et al. Blood. 2009 Feb 19;113(8):1768-77. doi: 10.1182/blood-2008-03-146084. Epub 2008 Oct 9. Blood. 2009. PMID: 18845793 Free article.

7

Clonal analysis of deletions on chromosome 20q and JAK2-V617F in MPD suggests that del20q acts independently and is not one of the predisposing mutations for JAK2-V617F.

Schaub FX, Jäger R, Looser R, Hao-Shen H, Hermouet S, Girodon F, Tichelli A, Gisslinger H, Kralovics R, Skoda RC. Schaub FX, et al. Blood. 2009 Feb 26;113(9):2022-7. doi: 10.1182/blood-2008-07-167056. Epub 2008 Dec 1. Blood. 2009. PMID: 19047681 Free article.

8

Clonal analysis of TET2 and JAK2 mutations suggests that TET2 can be a late event in the progression of myeloproliferative neoplasms.

Schaub FX, Looser R, Li S, Hao-Shen H, Lehmann T, Tichelli A, Skoda RC. Schaub FX, et al. Blood. 2010 Mar 11;115(10):2003-7. doi: 10.1182/blood-2009-09-245381. Epub 2010 Jan 8. Blood. 2010. PMID: 20061559 Free article.

9

Transition to homozygosity does not appear to provide a clonal advantage to hematopoietic progenitors carrying mutations in TET2.

Schaub FX, Lehmann T, Looser R, Hao-Shen H, Tichelli A, Skoda RC. Schaub FX, et al. Blood. 2011 Feb 10;117(6):2075-6. doi: 10.1182/blood-2010-11-316471. Blood. 2011. PMID: 21310937 Free article. No abstract available.

10

Differential effects of hydroxyurea and INC424 on mutant allele burden and myeloproliferative phenotype in a JAK2-V617F polycythemia vera mouse model.

Kubovcakova L, Lundberg P, Grisouard J, Hao-Shen H, Romanet V, Andraos R, Murakami M, Dirnhofer S, Wagner KU, Radimerski T, Skoda RC. Kubovcakova L, et al. Blood. 2013 Feb 14;121(7):1188-99. doi: 10.1182/blood-2012-03-415646. Epub 2012 Dec 20. Blood. 2013. PMID: 23264594 Free article.

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