Transition to homozygosity does not appear to provide a clonal advantage to hematopoietic progenitors carrying mutations in TET2

Blood. 2011 Feb 10;117(6):2075-6. doi: 10.1182/blood-2010-11-316471.
No abstract available

Publication types

  • Letter
  • Comment

MeSH terms

  • DNA-Binding Proteins / deficiency
  • DNA-Binding Proteins / genetics*
  • Dioxygenases
  • Hematologic Neoplasms / genetics*
  • Hematologic Neoplasms / pathology
  • Hematopoietic Stem Cells / metabolism*
  • Hematopoietic Stem Cells / pathology
  • Homozygote
  • Humans
  • Janus Kinase 2 / genetics
  • Mutation*
  • Proto-Oncogene Proteins / deficiency
  • Proto-Oncogene Proteins / genetics*

Substances

  • DNA-Binding Proteins
  • Proto-Oncogene Proteins
  • Dioxygenases
  • TET2 protein, human
  • JAK2 protein, human
  • Janus Kinase 2