Guy RK - Search Results

1

Chemical genetics of Plasmodium falciparum.

Guiguemde WA, Shelat AA, Bouck D, Duffy S, Crowther GJ, Davis PH, Smithson DC, Connelly M, Clark J, Zhu F, Jiménez-Díaz MB, Martinez MS, Wilson EB, Tripathi AK, Gut J, Sharlow ER, Bathurst I, El Mazouni F, Fowble JW, Forquer I, McGinley PL, Castro S, Angulo-Barturen I, Ferrer S, Rosenthal PJ, Derisi JL, Sullivan DJ, Lazo JS, Roos DS, Riscoe MK, Phillips MA, Rathod PK, Van Voorhis WC, Avery VM, Guy RK. Guiguemde WA, et al. Among authors: guy rk. Nature. 2010 May 20;465(7296):311-5. doi: 10.1038/nature09099. Nature. 2010. PMID: 20485428 Free PMC article.

2

Parallel synthesis and antimalarial screening of a 4-aminoquinoline library.

Madrid PB, Wilson NT, DeRisi JL, Guy RK. Madrid PB, et al. Among authors: guy rk. J Comb Chem. 2004 May-Jun;6(3):437-42. doi: 10.1021/cc0340473. J Comb Chem. 2004. PMID: 15132606 Free PMC article.

3

Discovery of potent thiosemicarbazone inhibitors of rhodesain and cruzain.

Fujii N, Mallari JP, Hansell EJ, Mackey Z, Doyle P, Zhou YM, Gut J, Rosenthal PJ, McKerrow JH, Guy RK. Fujii N, et al. Among authors: guy rk. Bioorg Med Chem Lett. 2005 Jan 3;15(1):121-3. doi: 10.1016/j.bmcl.2004.10.023. Bioorg Med Chem Lett. 2005. PMID: 15582423

4

Synthesis of ring-substituted 4-aminoquinolines and evaluation of their antimalarial activities.

Madrid PB, Sherrill J, Liou AP, Weisman JL, Derisi JL, Guy RK. Madrid PB, et al. Among authors: guy rk. Bioorg Med Chem Lett. 2005 Feb 15;15(4):1015-8. doi: 10.1016/j.bmcl.2004.12.037. Bioorg Med Chem Lett. 2005. PMID: 15686903

5

A solid-phase approach to the phallotoxins: total synthesis of [Ala7]-phalloidin.

Anderson MO, Shelat AA, Guy RK. Anderson MO, et al. Among authors: guy rk. J Org Chem. 2005 Jun 10;70(12):4578-84. doi: 10.1021/jo0503153. J Org Chem. 2005. PMID: 15932292

6

Parallel synthesis of 9-aminoacridines and their evaluation against chloroquine-resistant Plasmodium falciparum.

Anderson MO, Sherrill J, Madrid PB, Liou AP, Weisman JL, DeRisi JL, Guy RK. Anderson MO, et al. Among authors: guy rk. Bioorg Med Chem. 2006 Jan 15;14(2):334-43. doi: 10.1016/j.bmc.2005.08.017. Epub 2005 Oct 10. Bioorg Med Chem. 2006. PMID: 16216519 Free PMC article.

7

A high-throughput screening method to identify small molecule inhibitors of thyroid hormone receptor coactivator binding.

Arnold LA, Estébanez-Perpiñá E, Togashi M, Shelat A, Ocasio CA, McReynolds AC, Nguyen P, Baxter JD, Fletterick RJ, Webb P, Guy RK. Arnold LA, et al. Among authors: guy rk. Sci STKE. 2006 Jun 27;2006(341):pl3. doi: 10.1126/stke.3412006pl3. Sci STKE. 2006. PMID: 16804159

8

Incorporation of an intramolecular hydrogen-bonding motif in the side chain of 4-aminoquinolines enhances activity against drug-resistant P. falciparum.

Madrid PB, Liou AP, DeRisi JL, Guy RK. Madrid PB, et al. Among authors: guy rk. J Med Chem. 2006 Jul 27;49(15):4535-43. doi: 10.1021/jm0600951. J Med Chem. 2006. PMID: 16854059 Free PMC article.

9

Searching for new antimalarial therapeutics amongst known drugs.

Weisman JL, Liou AP, Shelat AA, Cohen FE, Guy RK, DeRisi JL. Weisman JL, et al. Among authors: guy rk. Chem Biol Drug Des. 2006 Jun;67(6):409-16. doi: 10.1111/j.1747-0285.2006.00391.x. Chem Biol Drug Des. 2006. PMID: 16882315 Free PMC article.

10

Design of a selective chemical probe for class I PDZ domains.

Fujii N, Shelat A, Hall RA, Guy RK. Fujii N, et al. Among authors: guy rk. Bioorg Med Chem Lett. 2007 Jan 15;17(2):546-8. doi: 10.1016/j.bmcl.2006.10.027. Epub 2006 Oct 17. Bioorg Med Chem Lett. 2007. PMID: 17074480

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