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Chronic pain causes Tau-mediated hippocampal pathology and memory deficits.
Mol Psychiatry. 2022 Nov;27(11):4385-4393. doi: 10.1038/s41380-022-01707-3. Epub 2022 Sep 2.
Mol Psychiatry. 2022.
PMID: 36056171
Chronic stress triggers divergent dendritic alterations in immature neurons of the adult hippocampus, depending on their ultimate terminal fields.
Dioli C, Patrício P, Sousa N, Kokras N, Dalla C, Guerreiro S, Santos-Silva MA, Rego AC, Pinto L, Ferreiro E, Sotiropoulos I.
Dioli C, et al.
Transl Psychiatry. 2019 Apr 26;9(1):143. doi: 10.1038/s41398-019-0477-7.
Transl Psychiatry. 2019.
PMID: 31028242
Free PMC article.
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Chronic pain inhibits autophagy in hippocampus while the analgetic drug, Gabapentin reverts this SNI-driven action.
Guerreiro SR, Guimarães MR, Silva JM, Dioli C, Vamvaka-Iakovou A, Sousa R, Gomes P, Megalokonomou A, Campos-Marques C, Cunha AM, Almeida A, Sousa N, Leite-Almeida H, Sotiropoulos I.
Guerreiro SR, et al.
Mol Psychiatry. 2022 Nov;27(11):4371. doi: 10.1038/s41380-022-01874-3.
Mol Psychiatry. 2022.
PMID: 36494573
No abstract available.
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Transition from Animal-Based to Human Induced Pluripotent Stem Cells (iPSCs)-Based Models of Neurodevelopmental Disorders: Opportunities and Challenges.
Guerreiro S, Maciel P.
Guerreiro S, et al.
Cells. 2023 Feb 7;12(4):538. doi: 10.3390/cells12040538.
Cells. 2023.
PMID: 36831205
Free PMC article.
Review.
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In vitro and in vivo evaluation of novel chromeno[2,3-d]pyrimidinones as therapeutic agents for triple negative breast cancer.
Carvalho L, de Lima FP, Cerqueira M, Silva A, Pontes O, Oliveira-Pinto S, Guerreiro S, Costa MD, Granja S, Maciel P, Longatto-Filho A, Baltazar F, Proença F, Costa M.
Carvalho L, et al.
RSC Med Chem. 2024 Mar 19;15(4):1362-1380. doi: 10.1039/d3md00682d. eCollection 2024 Apr 24.
RSC Med Chem. 2024.
PMID: 38665823
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Glucocorticoid receptor-dependent therapeutic efficacy of tauroursodeoxycholic acid in preclinical models of spinocerebellar ataxia type 3.
Duarte-Silva S, Da Silva JD, Monteiro-Fernandes D, Costa MD, Neves-Carvalho A, Raposo M, Soares-Cunha C, Correia JS, Nogueira-Goncalves G, Fernandes HS, Oliveira S, Ferreira-Fernandes AR, Rodrigues F, Pereira-Sousa J, Vilasboas-Campos D, Guerreiro S, Campos J, Meireles-Costa L, Rodrigues CMP, Cabantous S, Sousa SF, Lima M, Teixeira-Castro A, Maciel P.
Duarte-Silva S, et al.
J Clin Invest. 2024 Mar 1;134(5):e162246. doi: 10.1172/JCI162246.
J Clin Invest. 2024.
PMID: 38227368
Free PMC article.
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