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The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist.
van Bemmel JG, Galupa R, Gard C, Servant N, Picard C, Davies J, Szempruch AJ, Zhan Y, Żylicz JJ, Nora EP, Lameiras S, de Wit E, Gentien D, Baulande S, Giorgetti L, Guttman M, Hughes JR, Higgs DR, Gribnau J, Heard E. van Bemmel JG, et al. Among authors: galupa r. Nat Genet. 2019 Jun;51(6):1024-1034. doi: 10.1038/s41588-019-0412-0. Epub 2019 May 27. Nat Genet. 2019. PMID: 31133748 Free PMC article.
A Conserved Noncoding Locus Regulates Random Monoallelic Xist Expression across a Topological Boundary.
Galupa R, Nora EP, Worsley-Hunt R, Picard C, Gard C, van Bemmel JG, Servant N, Zhan Y, El Marjou F, Johanneau C, Diabangouaya P, Le Saux A, Lameiras S, Pipoli da Fonseca J, Loos F, Gribnau J, Baulande S, Ohler U, Giorgetti L, Heard E. Galupa R, et al. Mol Cell. 2020 Jan 16;77(2):352-367.e8. doi: 10.1016/j.molcel.2019.10.030. Epub 2019 Nov 20. Mol Cell. 2020. PMID: 31759823 Free PMC article.
Parental-to-embryo switch of chromosome organization in early embryogenesis.
Collombet S, Ranisavljevic N, Nagano T, Varnai C, Shisode T, Leung W, Piolot T, Galupa R, Borensztein M, Servant N, Fraser P, Ancelin K, Heard E. Collombet S, et al. Among authors: galupa r. Nature. 2020 Apr;580(7801):142-146. doi: 10.1038/s41586-020-2125-z. Epub 2020 Mar 25. Nature. 2020. PMID: 32238933
19 results