Fukuda T - Search Results

1

Discovery of DS42450411 as a potent orally active hepcidin production inhibitor: Design and optimization of novel 4-aminopyrimidine derivatives.

Fukuda T, Ishiyama T, Katagiri T, Ueda K, Muramatsu S, Hashimoto M, Aki A, Baba D, Watanabe K, Tanaka N. Fukuda T, et al. Bioorg Med Chem Lett. 2018 Nov 1;28(20):3333-3337. doi: 10.1016/j.bmcl.2018.09.010. Epub 2018 Sep 8. Bioorg Med Chem Lett. 2018. PMID: 30217414

2

Synthesis and SAR studies of 3,6-disubstituted indazole derivatives as potent hepcidin production inhibitors.

Fukuda T, Ueda K, Ishiyama T, Goto R, Muramatsu S, Hashimoto M, Watanabe K, Tanaka N. Fukuda T, et al. Bioorg Med Chem Lett. 2017 May 15;27(10):2148-2152. doi: 10.1016/j.bmcl.2017.03.056. Epub 2017 Mar 23. Bioorg Med Chem Lett. 2017. PMID: 28377056

3

Discovery of DS79182026: A potent orally active hepcidin production inhibitor.

Fukuda T, Goto R, Kiho T, Ueda K, Muramatsu S, Hashimoto M, Aki A, Watanabe K, Tanaka N. Fukuda T, et al. Bioorg Med Chem Lett. 2017 Aug 15;27(16):3716-3722. doi: 10.1016/j.bmcl.2017.07.004. Epub 2017 Jul 3. Bioorg Med Chem Lett. 2017. PMID: 28705644

4

Discovery of DS28120313 as a potent orally active hepcidin production inhibitor: Design and optimization of novel 4,6-disubstituted indazole derivatives.

Fukuda T, Goto R, Kiho T, Ueda K, Muramatsu S, Hashimoto M, Aki A, Watanabe K, Tanaka N. Fukuda T, et al. Bioorg Med Chem Lett. 2017 Dec 1;27(23):5252-5257. doi: 10.1016/j.bmcl.2017.10.031. Epub 2017 Oct 16. Bioorg Med Chem Lett. 2017. PMID: 29079471

5

Target identification of hepcidin production inhibitors by a combination of chemical proteomics and radioactive compound binding assay.

Sasaki M, Ueda K, Fukuda T, Tanaka N, Shimizu H, Kubota K. Sasaki M, et al. Among authors: fukuda t. Biochem Biophys Res Commun. 2018 Sep 18;503(4):2878-2884. doi: 10.1016/j.bbrc.2018.08.061. Epub 2018 Aug 21. Biochem Biophys Res Commun. 2018. PMID: 30139518

6

Synthesis and SAR studies of benzyl ether derivatives as potent orally active S1P₁ agonists.

Tsuji T, Suzuki K, Nakamura T, Goto T, Sekiguchi Y, Ikeda T, Fukuda T, Takemoto T, Mizuno Y, Kimura T, Kawase Y, Nara F, Kagari T, Shimozato T, Yahara C, Inaba S, Honda T, Izumi T, Tamura M, Nishi T. Tsuji T, et al. Among authors: fukuda t. Bioorg Med Chem. 2014 Aug 1;22(15):4246-56. doi: 10.1016/j.bmc.2014.05.035. Epub 2014 May 24. Bioorg Med Chem. 2014. PMID: 24909680

7

Potent and selective cathepsin K inhibitors.

Shinozuka T, Shimada K, Matsui S, Yamane T, Ama M, Fukuda T, Taki M, Takeda Y, Otsuka E, Yamato M, Mochizuki S, Ohhata K, Naito S. Shinozuka T, et al. Among authors: fukuda t. Bioorg Med Chem. 2006 Oct 15;14(20):6789-806. doi: 10.1016/j.bmc.2006.06.032. Epub 2006 Jul 13. Bioorg Med Chem. 2006. PMID: 16842999

8

4-Aminophenoxyacetic acids as a novel class of reversible cathepsin K inhibitors.

Shinozuka T, Shimada K, Matsui S, Yamane T, Ama M, Fukuda T, Taki M, Naito S. Shinozuka T, et al. Among authors: fukuda t. Bioorg Med Chem Lett. 2006 Mar 15;16(6):1502-5. doi: 10.1016/j.bmcl.2005.12.053. Epub 2005 Dec 27. Bioorg Med Chem Lett. 2006. PMID: 16380250

9

Arylamine based cathepsin K inhibitors: investigating P3 heterocyclic substituents.

Shinozuka T, Shimada K, Matsui S, Yamane T, Ama M, Fukuda T, Taki M, Takeda Y, Otsuka E, Yamato M, Naito S. Shinozuka T, et al. Among authors: fukuda t. Bioorg Med Chem. 2006 Oct 15;14(20):6807-19. doi: 10.1016/j.bmc.2006.06.031. Epub 2006 Jul 7. Bioorg Med Chem. 2006. PMID: 16829073

10

RS-1748, a novel CC chemokine receptor 4 antagonist, inhibits ovalbumin-induced airway inflammation in guinea pigs.

Nakagami Y, Kawase Y, Yonekubo K, Nosaka E, Etori M, Takahashi S, Takagi N, Fukuda T, Kuribayashi T, Nara F, Yamashita M. Nakagami Y, et al. Among authors: fukuda t. Biol Pharm Bull. 2010;33(6):1067-9. doi: 10.1248/bpb.33.1067. Biol Pharm Bull. 2010. PMID: 20522980 Free article.

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